Sugi Predict

Sugi Predict / Compounds / SCHEMBL290779

SCHEMBL290779

SCHEMBL290779

NC(CCCCC(=O)C(=O)O)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GSR P00390 2/20 0.59
▸ ARG2 P78540 4/20 0.53
▸ ARG1 P05089 3/20 0.53
▸ CYP1A2 P05177 3/20 0.52
▸ GRM8 O00222 1/20 0.52
▸ GRM6 O15303 1/20 0.52
▸ GRIN2D O15399 1/20 0.52
▸ GRIN3B O60391 1/20 0.52
▸ GRIK1 P39086 1/20 0.52
▸ GRM5 P41594 1/20 0.52
▸ GRIA1 P42261 1/20 0.52
▸ GRIA2 P42262 1/20 0.52
▸ GRIA3 P42263 1/20 0.52
▸ SLC1A3 P43003 1/20 0.52
▸ SLC1A2 P43004 1/20 0.52
▸ SLC1A1 P43005 1/20 0.52
▸ GRIA4 P48058 1/20 0.52
▸ GRIN1 Q05586 1/20 0.52
▸ GRIN2A Q12879 1/20 0.52
▸ GRIK2 Q13002 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3870750 0.93 GSR (0.56) GSRARG2ARG1CYP1A2GRM8
SCHEMBL261316 0.93 GSR (0.56) GSRARG2ARG1CYP1A2GRM8
Lysine SCHEMBL28250523 0.92 GSR (0.74) GSRARG2ARG1CYP1A2GRM8
Lysine SCHEMBL28250522 0.92 GSR (0.74) GSRARG2ARG1CYP1A2GRM8
(S)-2-Aminoadipic Acid SCHEMBL29106852 0.86 GSR (0.57) GSRARG2ARG1CYP1A2GRM8
Ornithine SCHEMBL8414153 0.86 GSR (0.64) GSRARG2ARG1CYP1A2GRM8
Ornithine Aketoglutarate SCHEMBL8414152 0.86 GSR (0.64) GSRARG2ARG1CYP1A2GRM8
SCHEMBL169988 0.84 GSR (0.65) GSRARG2ARG1CYP1A2GRM8
SCHEMBL169987 0.84 GSR (0.65) GSRARG2ARG1CYP1A2GRM8
Lysine SCHEMBL2020671 0.84 GSR (0.67) GSRARG2ARG1CYP1A2GRM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12577591-B2 Microorganisms and methods for increasing co-factors GENOMATICA, INC. (US) 2026-03-17 — — US claimed
CN-114728871-B Microorganisms and methods for reducing byproducts 基因组股份公司 2024-12-27 — — CN claimed
US-20230022727-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID GENOMATICA INC (US) 2023-01-26 — — US claimed
US-20220403420-A1 MICROORGANISMS AND METHODS FOR INCREASING CO-FACTORS AGAIN BIO APS (DK) 2022-12-22 — — US claimed
EP-4051657-A1 MICROORGANISMS AND METHODS FOR REDUCING BY-PRODUCTS Genomatica, Inc. (US) 2022-09-07 — — EP claimed
EP-4048781-A1 MICROORGANISMS AND METHODS FOR INCREASING CO-FACTORS Genomatica, Inc. (US) 2022-08-31 — — EP claimed
CN-114901815-A Microorganisms and methods for increasing cofactors 基因组股份公司 2022-08-12 — — CN claimed
CN-114728871-A Microorganisms and methods for reducing by-products 基因组股份公司 2022-07-08 — — CN claimed
US-11208673-B2 Microorganisms and methods for the biosynthesis of adipate, hexamethylenediamine and 6-aminocaproic acid GENOMATICA, INC. (US) 2021-12-28 — — US claimed
WO-2021086944-A1 MICROORGANISMS AND METHODS FOR RECUCING BY-PRODUCTS GENOMATICA, INC. (US) 2021-05-06 — — WO claimed
WO-2021081185-A1 MICROORGANISMS AND METHODS FOR INCREASING CO-FACTORS GENOMATICA, INC. (US) 2021-04-29 — — WO claimed
US-20190330670-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID AGAIN BIO APS (DK) 2019-10-31 — — US claimed
US-20130303723-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID AGAIN BIO APS (DK) 2013-11-14 — — US claimed
WO-2012177721-A1 MICROORGANISMS FOR PRODUCING 6-AMINOCAPROIC ACID GENOMATICA, INC. (US) 2012-12-27 — — WO claimed
EP-2427544-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID Genomatica, Inc. (US) 2012-03-14 — — EP claimed
US-20100317069-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID AGAIN BIO APS (DK) 2010-12-16 — — US claimed
WO-2010129936-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID GENOMATICA, INC. (US) 2010-11-11 — — WO claimed
US-12577594-B2 Engineered microorganisms and methods for improved aldehyde dehydrogenase activity GENOMATICA, INC. (US) 2026-03-17 — — US disclosed
US-20100317069-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID AGAIN BIO APS (DK) 2010-12-16 — — US disclosed
WO-2010129936-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID GENOMATICA, INC. (US) 2010-11-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577594-B2 Engineered microorganisms and methods for improved aldehyde dehydrogenase activity ACADM, ALDH7A1, ADSL GSR 1242/4885ARG2 667/4885ARG1 1103/4885
US-12577591-B2 Microorganisms and methods for increasing co-factors ABAT, HADHB, MMAB GSR 804/4885ARG2 1011/4885ARG1 4044/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.