Tetrahydrofuran

Tetrahydrofuran

SCHEMBL29078083

C1CCOC1.C=C(CC(=O)O)C(=O)OCCO

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL304508 0.86 TSHR (0.40) TSHRALOX15HSD17B10
Tetrahydrofuran SCHEMBL5508826 0.78 TSHR (0.49) TSHR
SCHEMBL1547902 0.78 TSHR (0.39) TSHRALOX15HSD17B10
SCHEMBL9419658 0.77 TSHR (0.47) TSHR
SCHEMBL4076300 0.77 TSHR (0.44) TSHRALOX15HSD17B10
SCHEMBL6855594 0.76 MEN1 (0.41) TSHRALOX15HSD17B10
SCHEMBL10524431 0.76 TSHR (0.42) TSHRALOX15HSD17B10
SCHEMBL2807013 0.75 ALOX15 (0.36) TSHRALOX15HSD17B10
SCHEMBL32679452 0.75 ALOX15 (0.39) TSHRALOX15HSD17B10
Tetrahydrofuran SCHEMBL22441892 0.74 TSHR (0.41) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109666121-B Hybrid dynamic cross-linked polymer and application thereof 厦门逍扬运动科技有限公司 2023-09-22 CN disclosed