SCHEMBL4076300

SCHEMBL4076300

C=C(CC(=O)O)C(=O)OCCCCOC(=O)C(=C)CC(=O)O

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
ALOX15 P16050 1/20 0.40
HSD17B10 Q99714 1/20 0.40
ALDH1A1 P00352 2/20 0.37
CYP3A4 P08684 1/20 0.37
TDP1 Q9NUW8 2/20 0.37
POLB P06746 1/20 0.37
APEX1 P27695 1/20 0.37
HTT P42858 1/20 0.37
LDHA P00338 1/20 0.35
SRR Q9GZT4 1/20 0.35
EPHX1 P07099 1/20 0.32
THRB P10828 1/20 0.32
ACHE P22303 6/20 0.31
HCAR2 Q8TDS4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27349377 0.95 ALOX15 (0.40) TSHRALOX15HSD17B10ALDH1A1CYP3A4
SCHEMBL1547902 0.92 TSHR (0.39) TSHRALOX15HSD17B10ALDH1A1CYP3A4
SCHEMBL26982459 0.90 ALDH1A1 (0.47) TSHRALOX15HSD17B10ALDH1A1CYP3A4
SCHEMBL1074983 0.90 TSHR (0.59) TSHRALDH1A1CYP3A4EPHX1ACHE
SCHEMBL10524431 0.90 TSHR (0.42) TSHRALOX15HSD17B10ALDH1A1CYP3A4
SCHEMBL2807013 0.90 ALOX15 (0.36) TSHRALOX15HSD17B10TDP1POLB
SCHEMBL5705570 0.89 TSHR (0.62) TSHRALDH1A1EPHX1ACHEHCAR2
SCHEMBL8356327 0.89 TSHR (0.62) TSHRALDH1A1EPHX1ACHEHCAR2
SCHEMBL6658549 0.89 TSHR (0.62) TSHRALDH1A1EPHX1ACHEHCAR2
SCHEMBL584464 0.89 TSHR (0.62) TSHRALDH1A1EPHX1ACHEHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0399755-B1 Light-sensitive composition and presensitized plate for use in making lithographic printing plates FUJI PHOTO FILM CO LTD (JP) 1994-03-30 EP claimed
US-20220002460-A1 BRANCHED POLYMERS THE UNIVERSITY OF LIVERPOOL (GB) 2022-01-06 US disclosed
EP-2738159-B1 MERCAPTO-BENZOPHENONE COMPOUNDS, COMPOSITIONS AND PREPARATION METHODS THEREOF INSIGHT HIGH TECH BEIJING CO LTD (CN) 2018-04-18 EP disclosed
US-9409861-B2 Mercapto benzophenone compounds, compositions and preparation method thereof Insight High Technology (Beijing) Co. Ltd. (CN) 2016-08-09 US disclosed
EP-3051349-A1 ALKALI-SOLUBLE POLYMER AND POLYMERIZABLE COMPOSITION THEREOF FUJIFILM Corporation (JP) 2016-08-03 EP disclosed
EP-1505441-B1 Alkali-soluble polymer, polymerizable composition comprising the same, negative image-recording material and process for image forming FUJIFILM CORP (JP) 2016-04-20 EP disclosed
US-20150246878-A1 MERCAPTO BENZOPHENONE COMPOUNDS, COMPOSITIONS AND PREPARATION METHOD THEREOF Insight High Technology (Beijing) Co. Ltd. (CN) 2015-09-03 US disclosed
US-9061979-B2 Mercapto benzophenone compounds, compositions and preparations method thereof Insight High Technology (Beijing) Co. Ltd. (CN) 2015-06-23 US disclosed
EP-2738159-A1 MERCAPTO-BENZOPHENONE COMPOUNDS, COMPOSITIONS AND PREPARATION METHODS THEREOF Insight High Technology Co., Ltd. (CN) 2014-06-04 EP disclosed
US-20130150479-A1 Mercapto Benzophenone Compounds, Compositions and Preparation Method Thereof Insight High Technology (Beijing) Co. Ltd. (CN) 2013-06-13 US disclosed
EP-0826692-B1 Molecular complexes as photoinitiators CIBA SC HOLDING AG (CH) 2003-03-05 EP disclosed
US-6516722-B2 Polymer converted from hydrophilic to hydrophobic by infrared radiation; crosslinkable by light or heat; decarboxylation FUJI PHOTO FILM CO., LTD. (JP) 2003-02-11 US disclosed
US-6455442-B1 EVAPORATING ULTRAVIOLET LIGHT ABSORBER OF HYDROXYPHENYL-S-TRIAZINE CLASS UNDER VACUUM WHILE EXPOSING IT TO PLASMA AND ALLOWING IT TO DEPOSIT ON SUBSTRATE CIBA SPECIALTY CHEMICALS CORPORATION 2002-09-24 US disclosed
US-20020100385-A1 Lithographic printing machine and lithographic printing method FUJIFILM CORPORATION (JP) 2002-08-01 US disclosed
EP-1082181-B1 PROCESS FOR THE PREPARATION OF UV PROTECTIVE COATINGS BY PLASMA-ENHANCED DEPOSITION CIBA SC HOLDING AG (CH) 2002-06-12 EP disclosed
EP-0826692-A2 Molecular complexes as photoinitiators Ciba SC Holding AG (CH) 1998-03-04 EP disclosed
EP-0332043-B1 Oxadiazole derivatives containing 4,6-bis-trichloromethyl-s-triazin-2-yl groups, process for their preparation and photosensitive mixture containing them HOECHST AG (DE) 1994-05-18 EP disclosed
EP-0332044-B1 HETEROCYCLIC COMPOUNDS CONTAINING 4,6-BIS-TRICHLOROMETHYL-S-TRIAZIN-2-YL GROUPS, PROCESS FOR THEIR PREPARATION AND PHOTOSENSITIVE MIXTURE CONTAINING THEM HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-16 EP disclosed
EP-0332044-A1 Heterocyclic compounds containing 4,6-bis-trichloromethyl-s-triazin-2-yl groups, process for their preparation and photosensitive mixture containing them HOECHST AKTIENGESELLSCHAFT (DE) 1989-09-13 EP disclosed
EP-0332043-A1 Oxadiazole derivatives containing 4,6-bis-trichloromethyl-s-triazin-2-yl groups, process for their preparation and photosensitive mixture containing them HOECHST AKTIENGESELLSCHAFT (DE) 1989-09-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150246878-A1 MERCAPTO BENZOPHENONE COMPOUNDS, COMPOSITIONS AND PREPARATION METHOD THEREOF MIF, TST, BMI1 TSHR 4866/4885ALOX15 98/4885HSD17B10 589/4885
US-20130150479-A1 Mercapto Benzophenone Compounds, Compositions and Preparation Method Thereof MIF, TST, BMI1 TSHR 4866/4885ALOX15 98/4885HSD17B10 589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.