Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | PDE1A | P54750 | 2/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1035189 | 0.93 | PI4KA (0.45) | HTR7GRIA2GRIN2APIK3CDPIK3CA | |
| SCHEMBL1346670 | 0.79 | GRIA2 (0.42) | GRIA2GRIN2APIK3CDPIK3CAPI4KA | |
| SCHEMBL1346577 | 0.77 | GRIA2 (0.43) | GRIA2GRIN2APIK3CDPIK3CAPI4KA | |
| SCHEMBL1524006 | 0.77 | PI4KA (0.40) | GRIA2GRIN2APIK3CDPIK3CAPI4KA | |
| SCHEMBL29079038 | 0.76 | PI4KA (0.38) | GRIA2GRIN2APIK3CDPIK3CAPI4KA | |
| SCHEMBL31108104 | 0.74 | FPR2 (0.51) | KDM4E | |
| SCHEMBL28163311 | 0.74 | HTR7 (0.62) | HTR7HPGDCNR1KDM4EALDH1A1 | |
| SCHEMBL27858932 | 0.74 | CNR1 (0.32) | HTR7KMT2ACNR1KDM4EALDH1A1 | |
| SCHEMBL1039375 | 0.72 | PI4KA (0.45) | GRIA2GRIN2APIK3CDPIK3CAPI4KA | |
| SCHEMBL26006408 | 0.72 | GRIA2 (0.48) | GRIA2GRIN2APIK3CDPIK3CAPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116640094-A | Compounds as PRMT1 inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2023-08-25 | — | — | CN | disclosed |