SCHEMBL29079336

SCHEMBL29079336

C#Cc1ccc(NC(=O)Cc2ccc(O)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 3/20 0.55
ACHE P22303 3/20 0.55
GAA P10253 2/20 0.54
NLRP3 Q96P20 2/20 0.49
EPHX2 P34913 1/20 0.49
SMN1; SMN2 Q16637 4/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
LMNA P02545 2/20 0.48
HTT P42858 1/20 0.48
CYP1A1 P04798 1/20 0.46
NPC1 O15118 2/20 0.45
RORC P51449 1/20 0.45
ADRB1 P08588 1/20 0.45
ADRB3 P13945 1/20 0.45
HPGD P15428 1/20 0.44
RAB9A P51151 1/20 0.44
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC1 Q13547 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29079343 0.85 TRPV1 (0.55) GAASMN1; SMN2MEN1KMT2ALMNA
SCHEMBL20746132 0.84 GAA (0.50) BCHEACHEGAAEPHX2SMN1; SMN2
SCHEMBL30624459 0.82 LMNA (0.59) NLRP3MEN1KMT2ALMNAHPGD
SCHEMBL29079361 0.82 LMNA (0.59) NLRP3MEN1KMT2ALMNAHPGD
SCHEMBL24467940 0.79 NLRP3 (0.73) BCHEACHEGAANLRP3EPHX2
SCHEMBL4451257 0.79 GAA (0.59) BCHEACHEGAANLRP3EPHX2
SCHEMBL3166771 0.79 SMN1; SMN2 (0.69) BCHEACHEGAANLRP3EPHX2
SCHEMBL2456637 0.79 SMN1; SMN2 (0.73) BCHEACHEGAANLRP3EPHX2
SCHEMBL4420812 0.78 EPHX2 (0.79) BCHEACHEGAAEPHX2SMN1; SMN2
SCHEMBL4420808 0.78 EPHX2 (0.79) BCHEACHEGAANLRP3EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117417279-A Phenoxyacetic acid compound, isomer thereof, pharmaceutically acceptable salt or solvate thereof, pharmaceutical composition and medical application 中国人民解放军军事科学院军事医学研究院 2024-01-19 CN disclosed
CN-116803977-A Preparation method and application of phenoxyacetic acid derivative 中国人民解放军军事科学院军事医学研究院 2023-09-26 CN disclosed