Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.81 |
| ▸ | NPC1 | O15118 | 4/20 | 0.81 |
| ▸ | MAPT | P10636 | 4/20 | 0.81 |
| ▸ | RAB9A | P51151 | 4/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.81 |
| ▸ | ALPG | P10696 | 1/20 | 0.81 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.79 |
| ▸ | MMP1 | P03956 | 13/20 | 0.71 |
| ▸ | MMP2 | P08253 | 13/20 | 0.71 |
| ▸ | MMP9 | P14780 | 13/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | MAOA | P21397 | 2/20 | 0.66 |
| ▸ | MAOB | P27338 | 2/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.65 |
| ▸ | RELA | Q04206 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13675873 | 0.86 | MEN1 (0.75) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL29167296 | 0.85 | MEN1 (0.70) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL8756825 | 0.81 | MMP1 (0.58) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL8756561 | 0.81 | MMP1 (0.58) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL8756556 | 0.81 | MMP1 (0.58) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL8756832 | 0.81 | MMP1 (0.58) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL29079362 | 0.81 | MEN1 (0.69) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL29079358 | 0.81 | MEN1 (0.69) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL11704923 | 0.76 | MMP1 (1.00) | MAPTMMP1MMP2MMP9MAOA | |
| SCHEMBL29277126 | 0.76 | MAPT (0.63) | MEN1KMT2ANPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117417279-A | Phenoxyacetic acid compound, isomer thereof, pharmaceutically acceptable salt or solvate thereof, pharmaceutical composition and medical application | 中国人民解放军军事科学院军事医学研究院 | 2024-01-19 | — | — | CN | disclosed |
| CN-116803977-A | Preparation method and application of phenoxyacetic acid derivative | 中国人民解放军军事科学院军事医学研究院 | 2023-09-26 | — | — | CN | disclosed |