SCHEMBL29167296

SCHEMBL29167296

CSc1cccc(NC(=O)/C=C/c2ccc(O)c(C)c2)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.70
KMT2A Q03164 5/20 0.70
MAPT P10636 4/20 0.70
NPC1 O15118 4/20 0.70
RAB9A P51151 4/20 0.70
SMN1; SMN2 Q16637 4/20 0.70
ALPG P10696 1/20 0.70
NPSR1 Q6W5P4 1/20 0.69
ALDH1A1 P00352 2/20 0.67
KDM4E B2RXH2 2/20 0.67
LMNA P02545 1/20 0.67
HTT P42858 1/20 0.67
MMP1 P03956 11/20 0.61
MMP2 P08253 11/20 0.61
MMP9 P14780 11/20 0.61
POLB P06746 1/20 0.58
NFKB1 P19838 1/20 0.56
NFKB2 Q00653 1/20 0.56
RELA Q04206 1/20 0.56
KDM1A O60341 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29079339 0.85 MEN1 (0.81) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL13675873 0.80 MEN1 (0.75) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL28003969 0.76 MMP1 (0.86) MMP1MMP2MMP9
SCHEMBL28003973 0.76 MMP1 (0.86) MMP1MMP2MMP9
SCHEMBL29079358 0.74 MEN1 (0.69) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL29079362 0.74 MEN1 (0.69) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL2262899 0.73 MMP1 (0.79) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL2262892 0.73 MMP1 (0.79) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL26038111 0.73 MMP1 (1.00) MMP1MMP2MMP9
SCHEMBL15396446 0.72 MMP1 (0.67) MEN1KMT2ANPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117417279-A Phenoxyacetic acid compound, isomer thereof, pharmaceutically acceptable salt or solvate thereof, pharmaceutical composition and medical application 中国人民解放军军事科学院军事医学研究院 2024-01-19 CN disclosed