Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 14/20 | 0.52 |
| ▸ | PPARG | P37231 | 10/20 | 0.48 |
| ▸ | PPARD | Q03181 | 6/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | FABP2 | P12104 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29079341 | 0.88 | PPARA (0.50) | PPARAPPARGALDH1A1SMN1; SMN2 | |
| SCHEMBL9614404 | 0.85 | PPARA (0.61) | PPARAPPARGPPARDHDAC1HDAC6 | |
| SCHEMBL29079337 | 0.83 | PPARA (0.53) | PPARAPPARGPPARDHDAC3HDAC4 | |
| SCHEMBL29079369 | 0.82 | PPARA (0.52) | PPARAPPARGPPARDHDAC3HDAC4 | |
| SCHEMBL29079329 | 0.80 | PPARA (0.56) | PPARAPPARGPPARDALDH1A1FABP2 | |
| SCHEMBL9614371 | 0.79 | PPARA (0.54) | PPARAPPARGPPARDALDH1A1FABP2 | |
| SCHEMBL29079343 | 0.78 | TRPV1 (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL16265104 | 0.78 | CYP1A1 (0.55) | PPARAPPARGALDH1A1 | |
| SCHEMBL29079331 | 0.76 | RAB9A (0.56) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL30624447 | 0.76 | NLRP3 (0.52) | PPARAPPARGPPARDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116803977-A | Preparation method and application of phenoxyacetic acid derivative | 中国人民解放军军事科学院军事医学研究院 | 2023-09-26 | — | — | CN | claimed |
| CN-117417279-A | Phenoxyacetic acid compound, isomer thereof, pharmaceutically acceptable salt or solvate thereof, pharmaceutical composition and medical application | 中国人民解放军军事科学院军事医学研究院 | 2024-01-19 | — | — | CN | disclosed |
| CN-116803977-A | Preparation method and application of phenoxyacetic acid derivative | 中国人民解放军军事科学院军事医学研究院 | 2023-09-26 | — | — | CN | disclosed |