SCHEMBL29079404

SCHEMBL29079404

CCCc1cc(CCl)c(O)c(CCl)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41
PTGS2 P35354 3/20 0.38
CYP3A4 P08684 1/20 0.38
HTT P42858 2/20 0.36
NPC1 O15118 1/20 0.36
HPGD P15428 1/20 0.36
MAPK1 P28482 1/20 0.36
RAB9A P51151 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ALOX5 P09917 1/20 0.36
DHFR P00374 1/20 0.36
GABRA1 P14867 3/20 0.35
GABRB2 P47870 3/20 0.35
GABRA5 P31644 1/20 0.35
GABRA3 P34903 1/20 0.35
GABRA2 P47869 1/20 0.35
HMGCR P04035 1/20 0.34
ALDH1A1 P00352 1/20 0.33
PTPN1 P18031 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10788028 0.88 NPC1 (0.52) PTGS2CYP3A4HTTNPC1HPGD
SCHEMBL10782672 0.88 DHFR (0.40) CNR1CNR2PTGS2CYP3A4ALOX5
SCHEMBL29079418 0.86 PTGS2 (0.57) PTGS2CYP3A4HTTNPC1HPGD
SCHEMBL29079429 0.84 PTGS2 (0.58) PTGS2CYP3A4HTTNPC1HPGD
SCHEMBL10782519 0.84 PTGS2 (0.58) PTGS2CYP3A4HTTNPC1HPGD
SCHEMBL29079405 0.84 PTGS2 (0.58) PTGS2CYP3A4HTTNPC1HPGD
SCHEMBL1023215 0.84 DHFR (0.45) CNR1CNR2PTGS2CYP3A4HTT
SCHEMBL1023550 0.82 DHFR (0.47) CNR1CNR2PTGS2CYP3A4HTT
SCHEMBL10788697 0.82 HSPA5 (0.47) PTGS2CYP3A4HPGDMAPK1ALOX5
SCHEMBL11330033 0.81 PTGS2 (0.55) PTGS2CYP3A4HTTALOX5ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116813900-A Double-end hydroxyl low molecular weight polyphenyl ether and synthesis method thereof 北京赛福瑞技术服务有限公司 2023-09-29 CN disclosed