SCHEMBL29079647

SCHEMBL29079647

CCN(c1cccc(O)c1)C(F)C(F)F

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.61
CYP3A4 P08684 2/20 0.61
TSHR P16473 2/20 0.47
LMNA P02545 3/20 0.37
ADRA1D P25100 2/20 0.37
ADRA1A P35348 2/20 0.37
ADRA1B P35368 2/20 0.37
HTR1A P08908 1/20 0.37
ADRA2A P08913 1/20 0.37
ADORA3 P0DMS8 1/20 0.37
CYP2D6 P10635 1/20 0.37
ADRA2B P18089 1/20 0.37
ADRA2C P18825 1/20 0.37
HTR2A P28223 1/20 0.37
HTR2C P28335 1/20 0.37
SLC6A4 P31645 1/20 0.37
CYP2C19 P33261 1/20 0.37
HRH1 P35367 1/20 0.37
SCN1A P35498 1/20 0.37
OPRK1 P41145 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11617480 0.81 MAPT (0.44) ALDH1A1CYP3A4TSHRCYP2D6CYP2C19
SCHEMBL7075432 0.81 ALDH1A1 (0.61) ALDH1A1CYP3A4TSHRLMNAADRA1D
SCHEMBL10957590 0.78 ALDH1A1 (0.58) ALDH1A1CYP3A4TSHRLMNAADRA1D
SCHEMBL124477 0.76 ALDH1A1 (1.00) ALDH1A1CYP3A4TSHRLMNAMAPT
SCHEMBL29379172 0.76 ALDH1A1 (1.00) ALDH1A1CYP3A4TSHRLMNAMAPT
Ethane SCHEMBL27716473 0.74 ALDH1A1 (0.96) ALDH1A1CYP3A4TSHRLMNAMAPT
Hydrochloric Acid SCHEMBL11588143 0.74 ALDH1A1 (0.96) ALDH1A1CYP3A4TSHRLMNAMAPT
SCHEMBL22166479 0.72 ALDH1A1 (0.81) ALDH1A1CYP3A4TSHRLMNAMAPT
SCHEMBL1670400 0.72 ALDH1A1 (0.63) ALDH1A1CYP3A4TSHRLMNAADRA1D
SCHEMBL9304794 0.71 ALDH1A1 (0.73) ALDH1A1CYP3A4TSHRLMNAADRA1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116648237-A Fluorescent dye 埃克波菲尔有限公司 2023-08-25 CN disclosed