Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.43 |
| ▸ | ESRRG | P62508 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6908896 | 0.91 | ALDH1A1 (0.63) | ALDH1A1CYP3A4TSHROPRM1OPRK1 | |
| SCHEMBL7072231 | 0.87 | ALDH1A1 (0.69) | ALDH1A1CYP3A4TSHROPRM1OPRK1 | |
| SCHEMBL124477 | 0.85 | ALDH1A1 (1.00) | ALDH1A1CYP3A4TSHROPRM1HTR7 | |
| SCHEMBL29379172 | 0.85 | ALDH1A1 (1.00) | ALDH1A1CYP3A4TSHROPRM1HTR7 | |
| SCHEMBL9322653 | 0.84 | ALDH1A1 (0.56) | ALDH1A1CYP3A4TSHROPRM1OPRK1 | |
| Ethane SCHEMBL27716473 | 0.83 | ALDH1A1 (0.96) | ALDH1A1CYP3A4TSHROPRM1HTR7 | |
| Hydrochloric Acid SCHEMBL11588143 | 0.83 | ALDH1A1 (0.96) | ALDH1A1CYP3A4TSHROPRM1HTR7 | |
| SCHEMBL28495975 | 0.82 | ALDH1A1 (0.53) | ALDH1A1CYP3A4TSHROPRM1OPRK1 | |
| SCHEMBL16398249 | 0.81 | ALDH1A1 (0.51) | ALDH1A1CYP3A4TSHROPRM1OPRK1 | |
| SCHEMBL11505004 | 0.81 | ALDH1A1 (0.46) | ALDH1A1CYP3A4TSHRLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0427572-B1 | Process for preparing N-alkylaminophenols and N,N-dialkylaminophenols | SUMITOMO CHEMICAL CO (JP) | 1994-04-27 | — | — | EP | disclosed |
| EP-0411817-B1 | Process for preparing N-alkyl-substituted aminophenols | SUMITOMO CHEMICAL CO (JP) | 1994-04-06 | — | — | EP | disclosed |
| US-5276193-A | Reductive alkylation, addition of carboxylic acid to prevent by-product formation | SUMITOMO CHEMICAL CO., LTD. (JP) | 1994-01-04 | — | — | US | disclosed |
| US-5202485-A | Catalytic reductive alkylation of aminophenol using aldehyde or ketone | SUMITOMO CHEMICAL CO., LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0427572-A1 | Process for preparing N-alkylaminophenols and N,N-dialkylaminophenols | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-05-15 | — | — | EP | disclosed |
| EP-0411817-A2 | Process for preparing N-alkyl-substituted aminophenols | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-02-06 | — | — | EP | disclosed |
| US-4665199-A | CHROMOGENS FOR HEAT-SENSITIVE OR PRESSURE-SENSITIVE RECORDING | SHIN NISSO KAKO CO., LTD. (JP) | 1987-05-12 | — | — | US | disclosed |
| US-4613879-A | 3-N-ISOBUTYLETHYLAMINO-6-METHYL-7-PHENYLAMINOFLUORAN | SHIN NISSO KAKO CO., LTD. (JP) | 1986-09-23 | — | — | US | disclosed |