Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
| ▸ | FPR2 | P25090 | 4/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | NPY4R | P50391 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 3/20 | 0.39 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29079661 | 0.95 | MEN1 (0.49) | MEN1BLMKMT2AUSP2POLB | |
| SCHEMBL14078000 | 0.89 | MEN1 (0.54) | MEN1BLMKMT2AUSP2POLB | |
| SCHEMBL14078001 | 0.86 | MEN1 (0.56) | MEN1BLMKMT2AUSP2POLB | |
| SCHEMBL12673518 | 0.84 | MEN1 (0.59) | MEN1BLMKMT2AUSP2POLB | |
| SCHEMBL24581468 | 0.84 | MEN1 (0.57) | MEN1BLMKMT2AUSP2POLB | |
| SCHEMBL12017847 | 0.83 | MEN1 (0.53) | MEN1BLMKMT2AUSP2POLB | |
| Hydrochloric Acid SCHEMBL29557664 | 0.83 | USP2 (0.53) | MEN1BLMKMT2AUSP2POLB | |
| SCHEMBL10098708 | 0.83 | MEN1 (0.54) | MEN1BLMKMT2AUSP2POLB | |
| SCHEMBL12019154 | 0.82 | MEN1 (0.52) | MEN1BLMKMT2AUSP2POLB | |
| Hydrochloric Acid SCHEMBL18617 | 0.82 | MEN1 (0.60) | MEN1BLMKMT2AUSP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4267680-A1 | FLUORESCENT DYES | Exopharm Limited (AU) | 2023-11-01 | — | — | EP | disclosed |
| CN-116648237-A | Fluorescent dye | 埃克波菲尔有限公司 | 2023-08-25 | — | — | CN | disclosed |
| WO-2022133552-A1 | FLUORESCENT DYES | Exopharm Limited (AU) | 2022-06-30 | — | — | WO | disclosed |