Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.38 |
| ▸ | ITGAV | P06756 | 19/20 | 0.38 |
| ▸ | ITGB6 | P18564 | 11/20 | 0.38 |
| ▸ | ITGB5 | P18084 | 7/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 7/20 | 0.35 |
| ▸ | ITGA5 | P08648 | 6/20 | 0.35 |
| ▸ | ITGB8 | P26012 | 6/20 | 0.35 |
| ▸ | ITGA8 | P53708 | 6/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2905461 | 0.95 | ITGB3 (0.34) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL2904181 | 0.90 | ITGB3 (0.40) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL2899754 | 0.84 | ITGB3 (0.38) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL2901789 | 0.82 | ITGB3 (0.37) | ITGB3ITGAVITGB6ITGA2B | |
| SCHEMBL2899491 | 0.79 | ITGB3 (0.50) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL2928710 | 0.77 | ITGB3 (0.43) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL2906558 | 0.77 | ITGB3 (0.41) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL2925476 | 0.76 | ITGB3 (0.42) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL2906704 | 0.74 | ITGB3 (0.38) | ITGB3ITGAVITGB5ITGA2BITGB1 | |
| SCHEMBL2925465 | 0.74 | ITGB3 (0.41) | ITGB3ITGAVITGB6ITGB5ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217569-A1 | ENANTIOSELECTIVE PROCESS FOR PREPARING A SUBSTITUTED ALKANOIC ACID | Janssen Pharmaceutica N.V. (BE) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009058314-A1 | ENANTIOSELECTIVE PROCESS FOR PREPARING A SUBSTITUTED ALKANOIC ACID | JANSSEN PHARMACEUTICA, N.V. (BE) | 2009-05-07 | — | — | WO | disclosed |