Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29079763 | 1.00 | ALDH1A1 (0.45) | ALDH1A1KMT2APOLBMEN1HCAR3 | |
| SCHEMBL29150025 | 0.85 | MAPT (0.55) | ALDH1A1KMT2APOLBMEN1HCAR3 | |
| SCHEMBL29150027 | 0.85 | MAPT (0.55) | ALDH1A1KMT2APOLBMEN1HCAR3 | |
| SCHEMBL27398353 | 0.85 | MAPT (0.47) | ALDH1A1KMT2APOLBMEN1HCAR3 | |
| SCHEMBL29480782 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KMT2APOLBMEN1HCAR3 | |
| SCHEMBL29052812 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KMT2APOLBMEN1HCAR3 | |
| SCHEMBL29052811 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KMT2APOLBMEN1HCAR3 | |
| SCHEMBL20266421 | 0.81 | HCAR3 (0.51) | ALDH1A1KMT2APOLBMEN1HCAR3 | |
| SCHEMBL20266420 | 0.81 | HCAR3 (0.51) | ALDH1A1KMT2APOLBMEN1HCAR3 | |
| SCHEMBL30200245 | 0.79 | HCAR3 (0.43) | ALDH1A1KMT2APOLBMEN1HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116406360-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2023-07-07 | — | — | CN | disclosed |
| EP-4204415-A1 | HETEROCYCLIC GLP-1 AGONISTS | Gasherbrum Bio, Inc. (US) | 2023-07-05 | — | — | EP | disclosed |
| WO-2022042691-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2022-03-03 | — | — | WO | disclosed |