Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 3/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29079914 | 0.84 | EPHX2 (0.36) | EPHX2GAAMAPTMEN1HTT | |
| SCHEMBL29079929 | 0.82 | ALDH1A1 (0.32) | PDE5AMEN1KMT2AMAPK1THRA | |
| SCHEMBL28242066 | 0.82 | GAA (0.37) | EPHX2GAAMAPTDRD2DRD3 | |
| SCHEMBL29008584 | 0.81 | EPHX2 (0.34) | EPHX2GAAMAPTMEN1KMT2A | |
| SCHEMBL13241463 | 0.79 | GAA (0.56) | GAAMAPTTHRATHRB | |
| SCHEMBL7294748 | 0.77 | GAA (0.61) | EPHX2GAAMAPTBRD4CREBBP | |
| SCHEMBL27358248 | 0.77 | GAA (0.61) | EPHX2GAAMAPTBRD4CREBBP | |
| SCHEMBL29079870 | 0.75 | PRMT5 (0.35) | EPHX2DRD2DRD3BRD4CREBBP | |
| Oxalic Acid SCHEMBL7294772 | 0.73 | MAPT (0.60) | EPHX2GAAMAPTHTTBRD4 | |
| SCHEMBL29057577 | 0.73 | GAA (0.39) | EPHX2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116648453-A | 5-and 6-azaindole compounds for inhibiting Bcr-Abl tyrosine kinase | 活力疗法公司 | 2023-08-25 | — | — | CN | disclosed |