Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CBR1 | P16152 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1145713 | 0.80 | TP53 (0.48) | TTRNR1I2LMNAPGRHSP90AA1 | |
| SCHEMBL1547622 | 0.79 | TDP1 (0.56) | TTRNR1I2LMNAPGRHSP90AA1 | |
| SCHEMBL829749 | 0.79 | TTR (0.56) | TTRNR1I2LMNAPGRHSP90AA1 | |
| SCHEMBL7186092 | 0.79 | TTR (0.75) | TTRNR1I2LMNAPGRHSP90AA1 | |
| SCHEMBL1684131 | 0.76 | SLC6A4 (0.44) | MAPTSLC6A2SLC6A3L3MBTL1S1PR4 | |
| SCHEMBL709651 | 0.76 | TSHR (0.49) | LMNAHPGDSLC6A2SLC6A3TP53 | |
| SCHEMBL3754064 | 0.76 | PPARG (0.45) | TTRNR1I2LMNAPGRHSP90AA1 | |
| SCHEMBL10664481 | 0.76 | ACHE (0.48) | LMNAMAPTHPGDTP53TDP1 | |
| SCHEMBL3283054 | 0.76 | S1PR4 (0.54) | MAPTHPGDTDP1TSHRHSD17B10 | |
| SCHEMBL23894348 | 0.75 | TTR (0.52) | TTRNR1I2LMNAPGRHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117886737-A | Spiroteine framework compound and preparation method and application thereof | 安徽农业大学 | 2024-04-16 | — | — | CN | claimed |
| WO-2022255900-A1 | CYSTEINYL LEUKOTRIENE RECEPTOR LIGANDS DIRECTED TOWARD THE TREATMENT OF INFLAMMATORY AND ONCOLOGICAL DISEASES | федеральное государственное автономное образовательное учреждение высшего образования "Московский физико-технический институт (национальный исследовательский университет)" | 2022-12-08 | — | — | WO | claimed |
| CN-104109118-B | Adjacent pyridine hydrazide derivatives and its preparation method and pharmaceutical composition and purposes | 中国医学科学院药物研究所 | 2018-07-24 | — | — | CN | claimed |
| CN-104109118-A | O-pyridine hydrazide derivatives, and preparation methods, pharmaceutical composition and application thereof | INST MATERIA MEDICA CAMS | 2014-10-22 | — | — | CN | claimed |
| CN-101874485-B | Use of diacylhydrazine compounds as bactericides | UNIV ZHEJIANG TECHNOLOGY | 2013-04-24 | — | — | CN | claimed |
| CN-101889577-B | Use of bishydrazide compounds as herbicide | UNIV ZHEJIANG TECHNOLOGY | 2013-04-24 | — | — | CN | claimed |
| US-8426401-B2 | Azetidinyl diamides as monoacylglycerol lipase inhibitors | JANSSEN PHARMACEUTICA, NV | 2013-04-23 | — | — | US | claimed |
| EP-2178373-B1 | HETEROCYCLES AS POTASSIUM CHANNEL MODULATORS | ICAGEN INC (US) | 2013-01-23 | — | — | EP | claimed |
| EP-2536718-A1 | HETEROCYCLES AS POTASSIUM CHANNEL MODULATORS | Icagen, Inc. (US) | 2012-12-26 | — | — | EP | claimed |
| EP-2421860-A1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | Janssen Pharmaceutica N.V. (BE) | 2012-02-29 | — | — | EP | claimed |
| US-4863954-A | Acyloxythiophene-carboxamide fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-05 | — | — | US | claimed |
| EP-0256137-A1 | BIS-DIOXOPIPERAZINE DERIVATIVES | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1988-02-24 | — | — | EP | claimed |
| EP-0241735-A2 | Acyloxythiophene carbon amide | BAYER AG (DE) | 1987-10-21 | — | — | EP | claimed |
| US-4650799-A | Bis-dioxopiperazine derivatives, process for their preparation, antitumor agents comprising them and compositions containing them | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-03-17 | — | — | US | claimed |
| EP-0095640-B1 | ALKYLENE-BRIDGED GUANIDINO-THIAZOLE DERIVATIVES, METHOD FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | BAYER AG (DE) | 1986-01-29 | — | — | EP | claimed |
| US-4515619-A | 1,2,3-Thiadiazole-5-yl-urea derivatives, agents containing these compounds with plant growth regulating and defoliating activity | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-05-07 | — | — | US | claimed |
| US-4491466-A | 1,2,3-Thiadiazole-5-yl-urea derivatives, processes for their use as plant growth regulating and defoliating agents | SCHERING AG (DE) | 1985-01-01 | — | — | US | claimed |
| US-4229578-A | BY REACTION OF ACID HALIDES AND XANTHATES | MONSANTO COMPANY (US) | 1980-10-21 | — | — | US | claimed |
| US-4020061-A | 3-Oxomethyl-2-(1-nitro-2-oxoethylidene)-tetrahydro-2H-1,3-thiazines | SHELL OIL COMPANY (US) | 1977-04-26 | — | — | US | claimed |
| US-4008249-A | HERBICIDE, PLANT GROWTH REGULATOR | BASF AKTIENGESELLSCHAFT (DT) | 1977-02-15 | — | — | US | claimed |