⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27404265 | 0.98 | TAAR1 (0.42) | — | |
| SCHEMBL11224676 | 0.87 | ALOX15 (0.48) | — | |
| Hydrochloric Acid SCHEMBL11222556 | 0.85 | ALOX15 (0.47) | — | |
| SCHEMBL27827138 | 0.84 | TAAR1 (0.41) | — | |
| SCHEMBL27827135 | 0.81 | CYP3A4 (0.49) | — | |
| SCHEMBL8368761 | 0.80 | TERT (0.44) | — | |
| SCHEMBL4731585 | 0.80 | ALOX15 (0.41) | — | |
| SCHEMBL28850765 | 0.80 | CYP1A2 (0.44) | — | |
| SCHEMBL585992 | 0.78 | — | — | |
| SCHEMBL28161824 | 0.78 | CYP1A2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006065842-A2 | 5,6,7,8-TETRAHYDROQUINOLINES AND RELATED COMPOUNDS AND USES THEREOF | SYNTA PHARMACEUTICALS CORP. (US) | 2006-06-22 | — | — | WO | claimed |
| EP-1663227-A2 | DIHYDROPYRIDINE COMPOUNDS FOR TREATING OR PREVENTING METABOLIC DISORDERS | Synta Pharmaceuticals Corporation (US) | 2006-06-07 | — | — | EP | claimed |
| WO-2005025507-A2 | DIHYDROPYRIDINE COMPOUNDS FOR TREATING OR PREVENTING METABOLIC DISORDERS | SYNTA PHAMACEUTICALS CORP. (US) | 2005-03-24 | — | — | WO | claimed |
| US-20260000777-A1 | NECTIN-4 ANTIBODY CONJUGATES AND USES THEREOF | ARARIS BIOTECH AG (CH) | 2026-01-01 | — | — | US | disclosed |
| WO-2022186034-A1 | RESIN COMPOSITION FOR CUTTING OFF BLUE LIGHT USING HOLLOW METAL OXIDE PARTICLES, AND USE THEREOF | 日本化薬株式会社 | 2022-09-09 | — | — | WO | disclosed |
| CN-112174903-B | Small molecule modulators of TLR8 | 清华大学 | 2022-07-12 | — | — | CN | disclosed |
| EP-3544627-A1 | IMMUNOGENIC COMPOSITIONS COMPRISING SBI PROTEIN AND USES THEREOF | The University Of Bath (GB) | 2019-10-02 | — | — | EP | disclosed |
| WO-2018096089-A1 | IMMUNOGENIC COMPOSITIONS COMPRISING SBI PROTEIN AND USES THEREOF | THE UNIVERSITY OF BATH (GB) | 2018-05-31 | — | — | WO | disclosed |
| US-20180094016-A1 | Triazole Compounds And Methods Of Making And Using The Same | BioVersys AG (CH) | 2018-04-05 | — | — | US | disclosed |
| US-20180094016-A1 | Triazole Compounds And Methods Of Making And Using The Same | BioVersys AG (CH) | 2018-04-05 | — | — | US | disclosed |
| EP-1934238-B1 | TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | MELINTA THERAPEUTICS INC (US) | 2017-06-28 | — | — | EP | disclosed |
| WO-2003040096-A2 | N, N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES | ELAN PHARMACEUTICALS, INC. (US) | 2003-05-15 | — | — | WO | disclosed |
| US-20030087880-A1 | Compound and pharmaceutical composition of antiplasmid effect and the preparation thereof | CSAPLAROS, LASZLO (HU) | 2003-05-08 | — | — | US | disclosed |
| EP-1287005-A2 | BENZOIC ACID ESTERS HAVING ANTIPLASMID EFFECT | Olah, Gabriella (HU) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001093843-A2 | BENZOIC ACID ESTERS HAVING ANTIPLASMID EFFECT | OLÁH, Gabriella (HU) | 2001-12-13 | — | — | WO | disclosed |
| EP-0561896-A1 | USE OF ANGIOTENSN II RECEPTOR ANTAGONISTS FOR THE PREPARATION OF A MEDICAMENT FOR IMPROVING COGNITIVE FUNCTION | SMITHKLINE BEECHAM PLC (GB) | 1993-09-29 | — | — | EP | disclosed |
| WO-1992010186-A1 | USE OF ANGIOTENSN II RECEPTOR ANTAGONISTS FOR THE PREPARATION OF A MEDICAMENT FOR IMPROVING COGNITIVE FUNCTION | SMITHKLINE BEECHAM PLC (GB) | 1992-06-25 | — | — | WO | disclosed |
| US-4831151-A | NEMATOCIDES | HOFFMANN-LA ROCHE INC. (US) | 1989-05-16 | — | — | US | disclosed |
| CN-86102906-A | Preparation 1, the method for the two substituted imidazole salt of 3- | — | 1987-02-11 | — | — | CN | disclosed |
| US-4248881-A | BACTERICIDES, FUNGICIDES | E. R. SQUIBB & SONS, INC. (US) | 1981-02-03 | — | — | US | disclosed |