Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.53 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.53 |
| ▸ | IGF1R | P08069 | 1/20 | 0.53 |
| ▸ | LTK | P29376 | 1/20 | 0.53 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.53 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.53 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.53 |
| ▸ | PRKX | P51817 | 1/20 | 0.53 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.53 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.53 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | ALDH1A3 | P47895 | 4/20 | 0.46 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 2/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.44 |
| ▸ | CLK2 | P49760 | 1/20 | 0.44 |
| ▸ | STK3 | Q13188 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28842472 | 0.79 | FGFR1 (0.53) | CLK4FGFR1NTRK1IGF1RLTK | |
| SCHEMBL29080578 | 0.79 | FGFR1 (0.53) | CLK4FGFR1NTRK1IGF1RLTK | |
| SCHEMBL1104800 | 0.79 | MAPT (0.61) | CLK4FGFR1NTRK1IGF1RLTK | |
| SCHEMBL7875511 | 0.75 | FGFR1 (0.53) | CLK4FGFR1NTRK1IGF1RLTK | |
| SCHEMBL7872399 | 0.75 | MAP2K1 (0.51) | CLK4FGFR1NTRK1IGF1RLTK | |
| SCHEMBL8505840 | 0.75 | FGFR1 (0.53) | CLK4FGFR1NTRK1IGF1RLTK | |
| SCHEMBL25346513 | 0.73 | NTRK1 (0.51) | CLK4FGFR1NTRK1IGF1RLTK | |
| Hydrochloric Acid SCHEMBL7870351 | 0.73 | FGFR1 (0.51) | CLK4FGFR1NTRK1IGF1RLTK | |
| SCHEMBL722447 | 0.73 | NTRK1 (0.48) | CLK4FGFR1NTRK1IGF1RLTK | |
| SCHEMBL13454268 | 0.72 | NTRK1 (0.47) | CLK4FGFR1NTRK1IGF1RLTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116813618-A | Amino-substituted imidazopyridine compound and synthesis method thereof | 郑州泰基鸿诺医药股份有限公司 | 2023-09-29 | — | — | CN | claimed |
| CN-116813618-A | Amino-substituted imidazopyridine compound and synthesis method thereof | 郑州泰基鸿诺医药股份有限公司 | 2023-09-29 | — | — | CN | disclosed |