SCHEMBL722447

SCHEMBL722447

[c]1ccc(-c2cn3c(-c4ccccc4)cccc3n2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NTRK1 P04629 1/20 0.48
IGF1R P08069 1/20 0.48
FGFR1 P11362 1/20 0.48
LTK P29376 1/20 0.48
MAP2K2 P36507 1/20 0.48
MAPK9 P45984 1/20 0.48
RPS6KA3 P51812 1/20 0.48
PRKX P51817 1/20 0.48
PRKCQ Q04759 1/20 0.48
TNK2 Q07912 1/20 0.48
CLK4 Q9HAZ1 1/20 0.48
MAP2K1 Q02750 2/20 0.47
CHEK1 O14757 5/20 0.45
MAP4K4 O95819 1/20 0.45
CSF1R P07333 1/20 0.45
PRKACA P17612 1/20 0.45
KDR P35968 1/20 0.45
CDK8 P49336 1/20 0.45
ACVR1 Q04771 1/20 0.45
MAP4K2 Q12851 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13454283 0.80 NTRK1 (0.47) NTRK1IGF1RFGFR1LTKMAP2K2
SCHEMBL13454268 0.80 NTRK1 (0.47) NTRK1IGF1RFGFR1LTKMAP2K2
SCHEMBL13133710 0.79 NTRK1 (0.46) NTRK1IGF1RFGFR1LTKMAP2K2
SCHEMBL722446 0.79 CHEK1 (0.43) NTRK1IGF1RFGFR1LTKMAP2K2
SCHEMBL29080578 0.77 FGFR1 (0.53) NTRK1IGF1RFGFR1LTKMAP2K2
SCHEMBL12920622 0.73 CHEK1 (0.50) NTRK1IGF1RFGFR1LTKMAP2K2
SCHEMBL28842472 0.73 FGFR1 (0.53) NTRK1IGF1RFGFR1LTKMAP2K2
SCHEMBL1104800 0.73 MAPT (0.61) NTRK1IGF1RFGFR1LTKMAP2K2
SCHEMBL29080571 0.73 CLK4 (0.53) NTRK1IGF1RFGFR1LTKMAP2K2
SCHEMBL103694 0.73 NUDT1 (0.47) MAP2K1CHEK1MAP4K4CSF1RPRKACA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10243151-B2 Organic semiconductor material and light-emitting element, light-emitting device, lighting system, and electronic device using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-03-26 US disclosed
US-20170250352-A1 Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-08-31 US disclosed
US-9620723-B2 Organic semiconductor material and light-emitting element, light-emitting device, lighting system, and electronic device using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-04-11 US disclosed
EP-2321862-B1 ORGANIC SEMICONDUCTOR MATERIAL AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, LIGHTING SYSTEM, AND ELECTRONIC DEVICE USING THE SAME SEMICONDUCTOR ENERGY LAB (JP) 2014-11-19 EP disclosed
US-8771843-B2 Fluorene derivative, organic compound, and light-emitting element, light-emitting device, and electronic device using the compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-07-08 US disclosed
US-20130112961-A1 Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-05-09 US disclosed
US-8343639-B2 Organic semiconductor material and light-emitting element, light-emitting device, lighting system, and electronic device using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-01-01 US disclosed
US-20120049768-A1 Fluorene Derivative, Organic Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-01 US disclosed
EP-2321862-A1 ORGANIC SEMICONDUCTOR MATERIAL AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, LIGHTING SYSTEM, AND ELECTRONIC DEVICE USING THE SAME Semiconductor Energy Laboratory Co, Ltd. (JP) 2011-05-18 EP disclosed
WO-2010027004-A1 ORGANIC SEMICONDUCTOR MATERIAL AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, LIGHTING SYSTEM, AND ELECTRONIC DEVICE USING THE SAME SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-03-11 WO disclosed
US-20100060155-A1 Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-03-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10243151-B2 Organic semiconductor material and light-emitting element, light-emitting device, lighting system, and electronic device using the same OXA1L, BECN1, MAP1LC3A NTRK1 916/4885IGF1R 2675/4885FGFR1 4050/4885
US-20170250352-A1 Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same OXA1L, BECN1, MAP1LC3A NTRK1 916/4885IGF1R 2675/4885FGFR1 4050/4885
US-20100060155-A1 Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same OXA1L, BECN1, MAP1LC3A NTRK1 916/4885IGF1R 2675/4885FGFR1 4050/4885
US-20120049768-A1 Fluorene Derivative, Organic Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Compound AFF2, MAPRE2, AFF4 NTRK1 942/4885IGF1R 3561/4885FGFR1 465/4885
US-20130112961-A1 Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same OXA1L, BECN1, MAP1LC3A NTRK1 916/4885IGF1R 2675/4885FGFR1 4050/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.