SCHEMBL1104800

SCHEMBL1104800

Cc1cccc2nc(-c3ccccc3)cn12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.61
PDE10A Q9Y233 3/20 0.58
KDM4E B2RXH2 8/20 0.56
ALDH1A1 P00352 6/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
HRH3 Q9Y5N1 1/20 0.54
RAB9A P51151 5/20 0.54
GAA P10253 4/20 0.54
NTRK1 P04629 1/20 0.53
IGF1R P08069 1/20 0.53
FGFR1 P11362 1/20 0.53
LTK P29376 1/20 0.53
MAP2K2 P36507 1/20 0.53
MAPK9 P45984 1/20 0.53
RPS6KA3 P51812 1/20 0.53
PRKX P51817 1/20 0.53
PRKCQ Q04759 1/20 0.53
TNK2 Q07912 1/20 0.53
CLK4 Q9HAZ1 1/20 0.53
HPGD P15428 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12787103 0.88 HRH3 (0.56) MAPTPDE10AKDM4EALDH1A1SMN1; SMN2
SCHEMBL13133691 0.86 HRH3 (0.56) MAPTPDE10AKDM4EALDH1A1SMN1; SMN2
SCHEMBL13325744 0.85 MAPT (0.59) MAPTPDE10AKDM4EALDH1A1SMN1; SMN2
SCHEMBL15101506 0.82 MAPT (0.55) MAPTPDE10AKDM4EALDH1A1SMN1; SMN2
SCHEMBL17953917 0.82 MAPT (0.55) MAPTPDE10AKDM4EALDH1A1SMN1; SMN2
SCHEMBL7703120 0.82 HRH3 (0.62) MAPTKDM4EALDH1A1SMN1; SMN2HRH3
SCHEMBL12970542 0.81 HRH3 (0.54) MAPTPDE10AKDM4EALDH1A1SMN1; SMN2
SCHEMBL30309621 0.80 HDAC6 (0.60) MAPTPDE10AKDM4EALDH1A1SMN1; SMN2
SCHEMBL29080578 0.79 FGFR1 (0.53) MAPTPDE10AKDM4EALDH1A1SMN1; SMN2
SCHEMBL28842472 0.79 FGFR1 (0.53) MAPTPDE10AKDM4EALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 385 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118812530-A Method for preparing imidazole pyridine compound by catalyzing lignin and model compound by Pd/C bi-component system 中国科学院大连化学物理研究所 2024-10-22 CN claimed
CN-118812530-A Method for preparing imidazole pyridine compound by catalyzing lignin and model compound by Pd/C bi-component system 中国科学院大连化学物理研究所 2024-10-22 CN disclosed
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes IDEMITSU KOSAN CO., LTD. (JP) 2023-07-04 US disclosed
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes IDEMITSU KOSAN CO., LTD. (JP) 2023-07-04 US disclosed
US-11069862-B2 Material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2021-07-20 US disclosed
CN-109734713-B 3-imido imidazo [1,2-a ] pyridine compound 东华理工大学 2021-06-04 CN disclosed
US-10833281-B2 Organic electroluminescence composition, material for organic electroluminescence element, solution of material for organic electroluminescence element, and organic electroluminescence element IDEMITSU KOSAN CO., LTD. (JP) 2020-11-10 US disclosed
US-10763442-B2 Compound, organic electroluminescent element material using same, organic electroluminescent element using this material, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2020-09-01 US disclosed
US-20190248804-A1 SPECIFICALLY SUBSTITUTED AZA-DIBENZOFURANS AND AZA-DIBENZOTHIOPHENES FOR ORGANIC ELECTRONIC DEVICES IDEMITSU KOSAN CO., LTD. (JP) 2019-08-15 US disclosed
US-20190161497-A1 SPECIFICALLY SUBSTITUTED BENZOFURO- AND BENZOTHIENOQUINOLINES FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO., LTD. (JP) 2019-05-30 US disclosed
US-20080100207-A1 Organoelectroluminescent compound and organoelectroluminescent device employing the same SAMSUNG DISPLAY CO., LTD. (KR) 2008-05-01 US disclosed
US-20080100207-A1 Organoelectroluminescent compound and organoelectroluminescent device employing the same SAMSUNG DISPLAY CO., LTD. (KR) 2008-05-01 US disclosed
US-20080079356-A1 Organoelectroluminescent compound and organoelectroluminescent device employing the same SAMSUNG DISPLAY CO., LTD. (KR) 2008-04-03 US disclosed
US-20080079356-A1 Organoelectroluminescent compound and organoelectroluminescent device employing the same SAMSUNG DISPLAY CO., LTD. (KR) 2008-04-03 US disclosed
US-20080076942-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-03-27 US disclosed
US-20080076942-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-03-27 US disclosed
US-20070273270-A1 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2007-11-29 US disclosed
US-20070273270-A1 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2007-11-29 US disclosed
US-20070275266-A1 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2007-11-29 US disclosed
US-20070275266-A1 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2007-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080076942-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME TYR, MAOA, DDC MAPT 82/4885PDE10A 2262/4885KDM4E 156/4885
US-10833281-B2 Organic electroluminescence composition, material for organic electroluminescence element, solution of material for organic electroluminescence element, and organic electroluminescence element SLCO4C1, SLCO2A1, SLCO1A2 MAPT 549/4885PDE10A 4053/4885KDM4E 3030/4885
US-20190248804-A1 SPECIFICALLY SUBSTITUTED AZA-DIBENZOFURANS AND AZA-DIBENZOTHIOPHENES FOR ORGANIC ELECTRONIC DEVICES CDY1; CDY1B, CDYL, CBX8 MAPT 4530/4885PDE10A 1953/4885KDM4E 212/4885
US-11069862-B2 Material for organic electroluminescence device and organic electroluminescence device using the same EPCAM, ILK, PPOX MAPT 792/4885PDE10A 3923/4885KDM4E 2903/4885
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes KCNQ2, KCNQ1, KCNQ4 MAPT 611/4885PDE10A 4030/4885KDM4E 962/4885
US-20080100207-A1 Organoelectroluminescent compound and organoelectroluminescent device employing the same PPOX, EML4, DDT MAPT 1300/4885PDE10A 2345/4885KDM4E 2854/4885
US-10763442-B2 Compound, organic electroluminescent element material using same, organic electroluminescent element using this material, and electronic device OR10J3, RER1, L1CAM MAPT 4731/4885PDE10A 3504/4885KDM4E 2101/4885
US-20190161497-A1 SPECIFICALLY SUBSTITUTED BENZOFURO- AND BENZOTHIENOQUINOLINES FOR ORGANIC LIGHT EMITTING DIODES KCNQ2, KCNQ1, KCNQ4 MAPT 611/4885PDE10A 4030/4885KDM4E 962/4885
US-20080079356-A1 Organoelectroluminescent compound and organoelectroluminescent device employing the same PPOX, EML4, ALPL MAPT 1667/4885PDE10A 1962/4885KDM4E 2677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.