SCHEMBL29080873

SCHEMBL29080873

Ic1ccn(C2CCO2)n1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CD274 Q9NZQ7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29099726 0.91 KMT2A (0.38) CD274
SCHEMBL28517402 0.73
SCHEMBL28757061 0.70 SIGMAR1 (0.36)
SCHEMBL31042946 0.68 CD274 (0.40) CD274
SCHEMBL31566399 0.68 HCAR1 (0.32)
SCHEMBL28752476 0.68 SMYD3 (0.34)
SCHEMBL28752475 0.68 SMYD3 (0.34)
SCHEMBL29063640 0.66 MEN1 (0.33)
SCHEMBL28459957 0.66 CYP1A2 (0.33)
SCHEMBL34468777 0.65 CD274 (0.40) CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111032046-B Pyruvate kinase modulators and uses thereof 安吉奥斯医药品有限公司 2023-09-26 CN disclosed