Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29080910 | 0.86 | RIPK1 (0.46) | RIPK1ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL18366144 | 0.82 | RIPK1 (0.46) | RIPK1MAPK1LCKALDH1A1HPGD | |
| SCHEMBL30587492 | 0.82 | RIPK1 (0.46) | RIPK1MAPK1LCKALDH1A1HPGD | |
| SCHEMBL30015041 | 0.80 | RIPK1 (0.63) | RIPK1MAPK1LCKALDH1A1HPGD | |
| SCHEMBL18366136 | 0.80 | RIPK1 (0.63) | RIPK1MAPK1LCKALDH1A1HPGD | |
| SCHEMBL18367362 | 0.79 | RIPK1 (0.42) | RIPK1MAPK1LCKALDH1A1HPGD | |
| SCHEMBL30092704 | 0.79 | RIPK1 (0.50) | RIPK1MAPK1LCKALDH1A1HPGD | |
| SCHEMBL18366444 | 0.79 | RIPK1 (0.50) | RIPK1MAPK1LCKALDH1A1HPGD | |
| SCHEMBL30587469 | 0.79 | RIPK1 (0.42) | RIPK1MAPK1LCKALDH1A1HPGD | |
| SCHEMBL18372660 | 0.79 | RIPK1 (0.50) | RIPK1MAPK1LCKALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111269221-B | Bicyclic lactams and methods of use thereof | 豪夫迈·罗氏有限公司 | 2023-09-26 | — | — | CN | disclosed |