Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.46 |
| ▸ | ASPH | Q12797 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 2/20 | 0.31 |
| ▸ | RXRB | P28702 | 2/20 | 0.31 |
| ▸ | RXRG | P48443 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29080908 | 0.86 | RIPK1 (0.44) | RIPK1KDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL18365947 | 0.80 | RIPK1 (0.46) | RIPK1ASPHKDM4EKDM8POLB | |
| SCHEMBL30587542 | 0.80 | RIPK1 (0.46) | RIPK1ASPHKDM4EKDM8POLB | |
| SCHEMBL18365949 | 0.78 | RIPK1 (0.67) | RIPK1ASPHKDM4EKDM8POLB | |
| SCHEMBL30014107 | 0.78 | RIPK1 (0.67) | RIPK1ASPHKDM4EKDM8POLB | |
| SCHEMBL30587490 | 0.78 | RIPK1 (0.67) | RIPK1ASPHKDM4EKDM8POLB | |
| SCHEMBL30092753 | 0.78 | RIPK1 (0.67) | RIPK1ASPHKDM4EKDM8POLB | |
| SCHEMBL19641479 | 0.78 | RIPK1 (0.67) | RIPK1ASPHKDM4EKDM8POLB | |
| SCHEMBL19641488 | 0.78 | RIPK1 (0.67) | RIPK1ASPHKDM4EKDM8POLB | |
| SCHEMBL18367366 | 0.77 | RIPK1 (0.45) | RIPK1ASPHKDM4EKDM8POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111269221-B | Bicyclic lactams and methods of use thereof | 豪夫迈·罗氏有限公司 | 2023-09-26 | — | — | CN | disclosed |