Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 4/20 | 0.40 |
| ▸ | DUSP5 | Q16690 | 2/20 | 0.40 |
| ▸ | DUSP6 | Q16828 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL21056187 | 0.95 | LMNA (0.48) | LMNATDP1PTPN1RAPGEF4DUSP5 | |
| SCHEMBL10840922 | 0.95 | LMNA (0.54) | LMNATDP1PTPN1RAPGEF4DUSP5 | |
| Lithium Ion SCHEMBL29172507 | 0.77 | KMT2A (0.53) | LMNATDP1ALDH1A1 | |
| SCHEMBL10452210 | 0.77 | LMNA (0.42) | LMNATDP1PTPN1RAPGEF4DUSP5 | |
| Lithium Ion SCHEMBL1036060 | 0.76 | GAA (0.62) | LMNATDP1RAPGEF4GAACA12 | |
| Lithium Ion SCHEMBL19434153 | 0.75 | LMNA (0.56) | LMNATDP1PTPN1RAPGEF4DUSP5 | |
| SCHEMBL8137089 | 0.75 | GAA (0.52) | LMNARAPGEF4GAATSHRALDH1A1 | |
| SCHEMBL12550497 | 0.74 | GAA (0.67) | LMNATDP1RAPGEF4GAACA2 | |
| SCHEMBL216137 | 0.74 | PTPN1 (0.50) | LMNATDP1PTPN1DUSP5DUSP6 | |
| Sulfuric Acid SCHEMBL6214534 | 0.74 | ALDH1A1 (0.50) | LMNATDP1RAPGEF4GAACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112795240-B | Ink for inkjet and image forming method | 京瓷办公信息系统株式会社 | 2023-09-26 | — | — | CN | disclosed |