Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30515141 | 0.70 | CHRNB4 (0.46) | CHRNB4CHRNA3SMN1; SMN2NISCHKDM4E | |
| SCHEMBL24367106 | 0.70 | CHRNB4 (0.42) | CHRNB4CHRNA3SMN1; SMN2NISCHKDM4E | |
| SCHEMBL895819 | 0.68 | CHRNB4 (0.67) | CHRNB4CHRNA3SMN1; SMN2NISCHKDM4E | |
| SCHEMBL24234068 | 0.67 | CHRNB4 (0.39) | CHRNB4CHRNA3 | |
| SCHEMBL26984249 | 0.61 | CHRNB4 (0.38) | CHRNB4CHRNA3NISCHKDM4EMAPT | |
| SCHEMBL165812 | 0.59 | CHRNB4 (0.87) | CHRNB4CHRNA3SMN1; SMN2NISCHKDM4E | |
| SCHEMBL28699058 | 0.59 | NPC1 (0.40) | CHRNB4CHRNA3SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL22546693 | 0.59 | NISCH (0.41) | CHRNB4CHRNA3SMN1; SMN2NISCHKDM4E | |
| SCHEMBL22546622 | 0.59 | NISCH (0.41) | CHRNB4CHRNA3SMN1; SMN2NISCHKDM4E | |
| SCHEMBL28299833 | 0.59 | NISCH (0.44) | CHRNB4CHRNA3SMN1; SMN2NISCHKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116568677-A | piperidin-1-yl-N-pyridin-3-yl-2-oxoacetamide derivatives useful for the treatment of MTAP deficiency and/or MTA accumulating cancers | 探戈医药股份有限公司 | 2023-08-08 | — | — | CN | disclosed |