Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29082171 | 0.85 | HTR1D (0.38) | HTR1DHTR1BALDH1A1MEN1KMT2A | |
| SCHEMBL29082509 | 0.78 | TAAR1 (0.34) | — | |
| SCHEMBL27368976 | 0.77 | KDM5A (0.40) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL28795205 | 0.73 | HTR1D (0.39) | HTR1DHTR1BALDH1A1MEN1KMT2A | |
| SCHEMBL23638591 | 0.71 | HPGD (0.42) | HTR1DHTR1BALDH1A1MEN1KMT2A | |
| SCHEMBL29021148 | 0.70 | NQO1 (0.42) | HTR1DHTR1BALDH1A1MEN1KMT2A | |
| SCHEMBL14709472 | 0.68 | HTR1D (0.33) | HTR1DHTR1BALDH1A1MEN1KMT2A | |
| SCHEMBL8137501 | 0.68 | FABP3 (0.42) | — | |
| SCHEMBL4938371 | 0.67 | IDO1 (0.48) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL7983095 | 0.66 | HTR1D (0.40) | HTR1DHTR1BALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116615413-A | Substituted 6, 7-dihydro-5H-benzo [7] rotaline compounds and derivatives thereof, method for the production and therapeutic use thereof | 赛诺菲 | 2023-08-18 | — | — | CN | disclosed |
| CN-116615414-A | Substituted 6, 7-dihydro-5H-benzo [7] rotaline compounds and derivatives thereof, method for the production and therapeutic use thereof | 赛诺菲 | 2023-08-18 | — | — | CN | disclosed |