SCHEMBL23638591

SCHEMBL23638591

COCc1c(C)cc(Br)cc1C

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.42
HSD17B10 Q99714 2/20 0.42
HTR1D P28221 1/20 0.38
HTR1B P28222 1/20 0.38
KDM4E B2RXH2 3/20 0.33
ALDH1A1 P00352 3/20 0.33
IDO1 P14902 1/20 0.32
NQO2 P16083 2/20 0.32
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
KMT2A Q03164 1/20 0.31
MAPT P10636 1/20 0.30
GAA P10253 1/20 0.30
ALOX15 P16050 1/20 0.30
APOBEC3G Q9HC16 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28795205 0.83 HTR1D (0.39) HTR1DHTR1BKDM4EALDH1A1IDO1
SCHEMBL893113 0.80 HPGD (0.44) HPGDHSD17B10KDM4EALDH1A1MEN1
SCHEMBL3807690 0.80 HPGD (0.44) HPGDHSD17B10HTR1DHTR1BKDM4E
SCHEMBL14008505 0.78 HPGD (0.47) HPGDHSD17B10ALDH1A1MEN1KMT2A
SCHEMBL12013420 0.77 ADRA2A (0.41) HPGDHSD17B10HTR1DHTR1BIDO1
SCHEMBL13626758 0.76 HPGD (0.42) HPGDHSD17B10KDM4EALDH1A1GAA
SCHEMBL15216746 0.76 ALDH1A1 (0.46) HPGDHSD17B10ALDH1A1MEN1KMT2A
SCHEMBL11930746 0.76 HPGD (0.42) HPGDHSD17B10KDM4EALDH1A1GAA
SCHEMBL12895706 0.74 HPGD (0.41) HPGDHSD17B10KDM4E
SCHEMBL19857663 0.74 ERN1 (0.40) KDM4EALDH1A1NQO2MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3848352-A1 BENZONITRILE DERIVATIVE, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING ELEMENT USING SAME Kyushu University, National University Corporation (JP) 2021-07-14 EP disclosed