Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 4/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 7/20 | 0.38 |
| ▸ | P2RX2 | Q9UBL9 | 7/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26977882 | 0.76 | ADORA2A (0.47) | DHFRNUDT1P2RX3P2RX2CCNA2 | |
| SCHEMBL2611023 | 0.75 | P2RX3 (0.51) | P2RX3P2RX2 | |
| SCHEMBL29082613 | 0.71 | NUDT1 (0.41) | DHFRNUDT1P2RX3P2RX2 | |
| SCHEMBL7891452 | 0.69 | NUDT1 (0.44) | NUDT1CCNA2CDK2CCNA1MAPT | |
| SCHEMBL29082597 | 0.69 | P2RX3 (0.36) | DHFRNUDT1P2RX3P2RX2 | |
| SCHEMBL30559753 | 0.68 | NUDT1 (0.44) | DHFRNUDT1P2RX3P2RX2 | |
| SCHEMBL26978100 | 0.68 | NUDT1 (0.44) | DHFRNUDT1P2RX3P2RX2 | |
| SCHEMBL31631823 | 0.67 | NUDT1 (0.59) | DHFRNUDT1P2RX3P2RX2 | |
| SCHEMBL4055122 | 0.67 | NUDT1 (0.59) | DHFRNUDT1P2RX3P2RX2 | |
| SCHEMBL2897696 | 0.67 | NUDT1 (0.58) | DHFRNUDT1P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116829550-A | Pyrimidine-2-ylsulfonamide derivatives | 豪夫迈·罗氏有限公司 | 2023-09-29 | — | — | CN | disclosed |