Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K7 | O43318 | 1/20 | 0.40 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 2/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3930316 | 0.83 | MYC (0.40) | MAP3K7TAB1KDM4EALDH1A1GAA | |
| SCHEMBL3930323 | 0.83 | MYC (0.40) | MAP3K7TAB1KDM4EALDH1A1GAA | |
| SCHEMBL26977866 | 0.82 | DPP4 (0.47) | KDM4EALDH1A1CNKSR1CA12CA1 | |
| SCHEMBL30559668 | 0.82 | DPP4 (0.47) | KDM4EALDH1A1CNKSR1CA12CA1 | |
| SCHEMBL21411388 | 0.78 | EIF2AK2 (0.41) | MAP3K7TAB1KDM4EALDH1A1GAA | |
| SCHEMBL21411389 | 0.78 | EIF2AK2 (0.41) | MAP3K7TAB1KDM4EALDH1A1GAA | |
| SCHEMBL13736042 | 0.77 | NUDT1 (0.39) | KDM4EALDH1A1KMT2ANUDT1 | |
| SCHEMBL4144963 | 0.76 | THRB (0.38) | MAP3K7TAB1KDM4EALDH1A1GAA | |
| SCHEMBL4144972 | 0.76 | THRB (0.38) | MAP3K7TAB1KDM4EALDH1A1GAA | |
| SCHEMBL26977841 | 0.75 | MIF (0.42) | KDM4EALDH1A1GAATHRBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116829550-A | Pyrimidine-2-ylsulfonamide derivatives | 豪夫迈·罗氏有限公司 | 2023-09-29 | — | — | CN | disclosed |