Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | AADAC | P22760 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29083255 | 0.88 | MEN1 (0.45) | ALDH1A1SMN1; SMN2LMNAPOLBNPC1 | |
| SCHEMBL29788823 | 0.86 | GCK (0.56) | ALDH1A1SMN1; SMN2LMNAPOLBNPC1 | |
| SCHEMBL2551479 | 0.86 | GCK (0.56) | ALDH1A1SMN1; SMN2LMNAPOLBNPC1 | |
| SCHEMBL29083248 | 0.85 | POLB (0.42) | ALDH1A1SMN1; SMN2LMNAPOLBNPC1 | |
| SCHEMBL29083242 | 0.84 | KDR (0.52) | METKDR | |
| SCHEMBL13504178 | 0.83 | RAB9A (0.53) | ALDH1A1SMN1; SMN2LMNAMAPK1POLB | |
| SCHEMBL29083252 | 0.82 | GCK (0.43) | METKDRMAPTGCKRIOK2 | |
| SCHEMBL16038555 | 0.82 | CSF1R (0.45) | SMN1; SMN2POLBNPC1RAB9AMET | |
| SCHEMBL29083258 | 0.82 | KMT2A (0.44) | LMNAMETKDRGCKKMT2A | |
| SCHEMBL23795626 | 0.79 | MEN1 (0.43) | ALDH1A1SMN1; SMN2LMNAPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907339-B | 4- (4-aminophenoxy) pyridin-2-amine derivatives and use thereof | 成都奥睿药业有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-114907339-A | 4- (4-aminophenoxy) pyridin-2-amine derivatives and uses thereof | 成都奥睿药业有限公司 | 2022-08-16 | — | — | CN | disclosed |