Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | GCK | P35557 | 4/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23795626 | 0.90 | MEN1 (0.43) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL23795618 | 0.89 | MEN1 (0.42) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL2551479 | 0.89 | GCK (0.56) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL29788823 | 0.89 | GCK (0.56) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL29083232 | 0.88 | ALDH1A1 (0.42) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL29083248 | 0.88 | POLB (0.42) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL29083242 | 0.87 | KDR (0.52) | BRAFKDR | |
| SCHEMBL13504178 | 0.86 | RAB9A (0.53) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL2562936 | 0.85 | MAPK14 (0.49) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL29662429 | 0.85 | MAPK14 (0.49) | MEN1KMT2APOLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907339-B | 4- (4-aminophenoxy) pyridin-2-amine derivatives and use thereof | 成都奥睿药业有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-114907339-A | 4- (4-aminophenoxy) pyridin-2-amine derivatives and uses thereof | 成都奥睿药业有限公司 | 2022-08-16 | — | — | CN | disclosed |