SCHEMBL2908396

SCHEMBL2908396

CCCCCCC(Cl)(Cl)C(Cl)(Cl)Cl

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FDPS P14324 11/20 0.46
SMPD1 P17405 4/20 0.46
GGPS1 O95749 7/20 0.44
TSHR P16473 2/20 0.44
THRB P10828 1/20 0.44
LPAR1 Q92633 1/20 0.41
LPAR3 Q9UBY5 1/20 0.41
ALDH1A1 P00352 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28424130 1.00 FDPS (0.46) FDPSSMPD1GGPS1TSHRTHRB
SCHEMBL28493935 1.00 FDPS (0.46) FDPSSMPD1GGPS1TSHRTHRB
SCHEMBL15813134 0.97 FDPS (0.44) FDPSSMPD1GGPS1TSHRTHRB
Water SCHEMBL27617953 0.93 FDPS (0.42) FDPSSMPD1GGPS1TSHRTHRB
SCHEMBL25297461 0.88 FDPS (0.42) FDPSSMPD1GGPS1TSHRTHRB
SCHEMBL8204492 0.81 TSHR (0.42) FDPSSMPD1GGPS1TSHRTHRB
SCHEMBL10593474 0.79 CES2 (0.43) FDPSSMPD1GGPS1TSHRTHRB
SCHEMBL16969610 0.79 FDPS (0.45) FDPSSMPD1GGPS1
SCHEMBL16970228 0.79 FDPS (0.45) FDPSSMPD1GGPS1
SCHEMBL16969644 0.79 FDPS (0.45) FDPSSMPD1GGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1516597-A1 DRUG ELUTING STENT Microport Medical (Shanghai) Co., Ltd. (CN) 2005-03-23 EP claimed
US-20160220738-A1 PROGESTERONE-CONTAINING COMPOSITIONS AND DEVICES JACKSON GREGG A (US) 2016-08-04 US disclosed
US-20130245570-A1 PROGESTERONE-CONTAINING COMPOSITIONS AND DEVICES JACKSON GREGG A (US) 2013-09-19 US disclosed
US-20100272779-A1 PROGESTERONE-CONTAINING COMPOSITIONS AND DEVICES JACKSON GREGG A 2010-10-28 US disclosed
EP-2219554-A1 PROGESTERONE-CONTAINING COMPOSITIONS AND DEVICES Jackson, Gregg A. (US) 2010-08-25 EP disclosed
WO-2009070794-A1 PROGESTERONE-CONTAINING COMPOSITIONS AND DEVICES JACKSON GREGG A (US) 2009-06-04 WO disclosed
EP-1516597-A1 DRUG ELUTING STENT Microport Medical (Shanghai) Co., Ltd. (CN) 2005-03-23 EP disclosed
US-20050043788-A1 Drug-eluting stent MICROPORT MEDICAL CO., LTD. 2005-02-24 US disclosed
US-20050033414-A1 Drug-eluting stent with multi-layer coatings MICROPORT MEDICAL CO. LTD. 2005-02-10 US disclosed