Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL3986375 | 0.97 | TDP1 (0.50) | TDP1TSHRNAPRTCHRNB2CHRNA4 | |
| Pyridine SCHEMBL9655437 | 0.92 | TSHR (0.45) | TDP1TSHRNAPRTCHRNB2CHRNA4 | |
| Pyridine SCHEMBL3508428 | 0.90 | TSHR (0.43) | TDP1TSHRNAPRTCHRNB2CHRNA4 | |
| Pyridine SCHEMBL8356836 | 0.90 | TDP1 (0.43) | TDP1TSHRNAPRTCHRNB2CHRNA4 | |
| Pyridine SCHEMBL9655441 | 0.88 | TSHR (0.41) | TDP1TSHRNAPRTCHRNB2CHRNA4 | |
| Pyridine SCHEMBL4807582 | 0.88 | TSHR (0.41) | TDP1TSHRNAPRTCHRNB2CHRNA4 | |
| Pyridine SCHEMBL11393043 | 0.86 | TSHR (0.39) | TDP1TSHRNAPRTHTTKDM4E | |
| Pyrazine SCHEMBL28358879 | 0.84 | HRH3 (0.32) | TDP1CHRNB2CHRNA4HTTKDM4E | |
| Pyridine SCHEMBL15019090 | 0.84 | KCNH2 (0.41) | TDP1TSHRNAPRTCHRM2HTR1A | |
| Toluene SCHEMBL536968 | 0.82 | TSHR (0.44) | TDP1TSHRNAPRTCHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 359 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478604-A | Antifouling wear-resistant environment-friendly floor paint | 广东坚派新材料有限公司 | 2023-07-25 | — | — | CN | claimed |
| CN-115926459-A | Preparation method of quick freeze-drying polyimide aerogel | 南京工业大学 | 2023-04-07 | — | — | CN | claimed |
| CN-113429868-A | Modified polyurethane coating and preparation method thereof | 武汉度美迪新能源科技有限公司 | 2021-09-24 | — | — | CN | claimed |
| CN-112250620-A | Synthesis method of pirfenidone | 沈阳三九药业有限公司 | 2021-01-22 | — | — | CN | claimed |
| CN-110305000-A | A kind of daunomycinone midbody compound | 鲁南制药集团股份有限公司 | 2019-10-08 | — | — | CN | claimed |
| WO-2016098015-A1 | NEW EFFICIENT METHODS FOR THE SYNTHESIS OF TAXANE DERIVATIVES SUCH AS DOCETAXEL AND THEIR STRUCTURAL ANALOGOUS, AND A METHOD FOR THE PREPARATION THEREOF | KARIMIAN KHASHAYAR (IR) | 2016-06-23 | — | — | WO | claimed |
| EP-2855432-A1 | PROCESS FOR PREPARATION OF (1S, 3S, 5S)-2-[(2S)-2-AMINO-2-(3-HYDROXY-1-ADAMANTYL) ACETYL]-2-AZABICYCLO [3.1.0]HEXANE-3-CARBONITRILE | Davuluri, Ramamohan Rao (IN) | 2015-04-08 | — | — | EP | claimed |
| WO-2013179297-A1 | PROCESS FOR PREPARATION OF (1S, 3S, 5S)-2-[(2S)-2-AMINO-2-(3-HYDROXY-1-ADAMANTYL) ACETYL]-2-AZABICYCLO [3.1.0] HEXANE-3-CARBONITRILE | RAO DAVULURI RAMAMOHAN (IN) | 2013-12-05 | — | — | WO | claimed |
| CN-102977166-A | 13-thioether substituted pleocidin derivative and preparation method thereof | HUNAN RES INST CHEMICAL IND | 2013-03-20 | — | — | CN | claimed |
| CN-102093254-A | Preparation method of 3-(2,2,2-trimethylhydrazine)propionate dihydrate | UNIV SHAOXING | 2011-06-15 | — | — | CN | claimed |
| CN-101973909-A | Preparation method of mildronate | UNIV SHAOXING | 2011-02-16 | — | — | CN | claimed |
| JP-60041649-A | — | — | None | — | — | JP | disclosed |
| JP-62249944-A | — | — | None | — | — | JP | disclosed |
| JP-5241212-A | — | — | None | — | — | JP | disclosed |
| CN-122094943-A | Novel 1,2, 4-oxadiazoles as fungicides | — | 2026-05-26 | — | — | CN | disclosed |
| US-4029492-A | Novel 1,2-dialkylpyrazolium compounds having 3-(or 3,5-) nitrogen-containing heterocyclic group as herbicides | AMERICAN CYANAMID COMPANY (US) | 1977-06-14 | — | — | US | disclosed |
| US-4026909-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1977-05-31 | — | — | US | disclosed |
| US-4016184-A | PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1977-04-05 | — | — | US | disclosed |
| US-4013695-A | PROSTAGLANDINS, HYPOTENSIVES, OXYTOCICS, ANTISECRETORY AND ANTIULCER AGENTS, REPRODUCTION CONTROL | THE UPJOHN COMPANY (US) | 1977-03-22 | — | — | US | disclosed |
| US-3931173-A | HYPOLIPIDEMIC | RICHARDSON-MERRELL INC. (US) | 1976-01-06 | — | — | US | disclosed |