Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL290841 | 0.88 | TDP1 (0.53) | TSHRNAPRTTDP1CHRNB2CHRNA4 | |
| Pyridine SCHEMBL9655437 | 0.86 | TSHR (0.45) | TSHRNAPRTTDP1CHRNB2CHRNA4 | |
| Pyridine SCHEMBL3986375 | 0.85 | TDP1 (0.50) | TSHRNAPRTTDP1CHRNB2CHRNA4 | |
| Pyridine SCHEMBL3508428 | 0.79 | TSHR (0.43) | TSHRNAPRTTDP1CHRNB2CHRNA4 | |
| Pyridine SCHEMBL8356836 | 0.79 | TDP1 (0.43) | TSHRNAPRTTDP1CHRNB2CHRNA4 | |
| Pyridine SCHEMBL4807582 | 0.77 | TSHR (0.41) | TSHRNAPRTTDP1CHRNB2CHRNA4 | |
| SCHEMBL9403568 | 0.77 | — | — | |
| Pyridine SCHEMBL11393043 | 0.76 | TSHR (0.39) | TSHRNAPRTTDP1 | |
| Pyrazine SCHEMBL28358879 | 0.74 | HRH3 (0.32) | TDP1CHRNB2CHRNA4 | |
| Pyridine SCHEMBL15019090 | 0.74 | KCNH2 (0.41) | TSHRNAPRTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151333-A | Containing imine derivative | NIPPON ZEON CO., LTD (JP) | 1992-09-29 | — | — | US | disclosed |