Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2908481 | 0.85 | HSP90AA1 (0.45) | KIF18ACA12CA1CA2CA7 | |
| SCHEMBL1992257 | 0.82 | PTGES2 (0.47) | PGRHPGDALDH1A1L3MBTL1HTT | |
| SCHEMBL2907645 | 0.81 | ALDH1A1 (0.47) | PGRKIF18APTGDR2ALDH1A1GAA | |
| SCHEMBL2902261 | 0.78 | PTGDR2 (0.41) | PTGDR2HPGDKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL14544600 | 0.78 | FFAR1 (0.46) | PTGDR2 | |
| SCHEMBL3421956 | 0.78 | PTGDR2 (0.43) | KIF18APTGDR2KDM4EALDH1A1GAA | |
| SCHEMBL1991221 | 0.77 | PTGDR2 (0.64) | PTGDR2 | |
| SCHEMBL1996728 | 0.73 | PPARG (0.42) | PTGDR2NPSR1 | |
| SCHEMBL777912 | 0.71 | CA12 (0.53) | CA12CA1CA2CA7CA13 | |
| SCHEMBL2908737 | 0.69 | FEN1 (0.43) | PTGDR2HPGDKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937633-B1 | BIPHENYLOXYACETIC ACID DERIVATIVES FOR THE TREATMENT OF RESPIRATORY DISEASE | ASTRAZENECA AB (SE) | 2010-08-04 | — | — | EP | claimed |