Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | ACLY | P53396 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2908480 | 0.85 | PGR (0.39) | HSP90AA1HSP90AB1ERBB2ACLYCA1 | |
| SCHEMBL1994313 | 0.81 | PTGS2 (0.49) | HSP90AA1HSP90AB1ERBB2ACLYCA1 | |
| SCHEMBL1992257 | 0.81 | PTGES2 (0.47) | MEN1LMNAMAPTHPGDKMT2A | |
| SCHEMBL2902261 | 0.79 | PTGDR2 (0.41) | POLBMEN1LMNAMAPTHPGD | |
| SCHEMBL14544600 | 0.79 | FFAR1 (0.46) | LMNAPTGDR2 | |
| SCHEMBL1991221 | 0.78 | PTGDR2 (0.64) | PTGDR2 | |
| SCHEMBL1990235 | 0.78 | PTGDR2 (0.45) | HSP90AA1HSP90AB1ERBB2ACLYPOLB | |
| SCHEMBL1993027 | 0.74 | MEN1 (0.51) | POLBGAAMEN1MAPK1KMT2A | |
| SCHEMBL1996728 | 0.74 | PPARG (0.42) | KMT2ANPSR1PTGDR2 | |
| SCHEMBL1993521 | 0.74 | POLB (0.46) | POLBGAAMEN1KMT2APTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937633-B1 | BIPHENYLOXYACETIC ACID DERIVATIVES FOR THE TREATMENT OF RESPIRATORY DISEASE | ASTRAZENECA AB (SE) | 2010-08-04 | — | — | EP | claimed |