⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28595610 | 0.88 | HTR2C (0.32) | — | |
| SCHEMBL28587057 | 0.86 | DPP4 (0.34) | — | |
| SCHEMBL28585822 | 0.85 | NFKB1 (0.31) | — | |
| SCHEMBL23087060 | 0.82 | MME (0.31) | — | |
| SCHEMBL8140265 | 0.76 | USP2 (0.41) | — | |
| SCHEMBL31031022 | 0.76 | ASGR1 (0.36) | — | |
| SCHEMBL21997499 | 0.75 | USP2 (0.35) | — | |
| SCHEMBL23572515 | 0.74 | MEN1 (0.32) | — | |
| SCHEMBL23282418 | 0.72 | ASGR1 (0.40) | — | |
| SCHEMBL22957198 | 0.72 | PDK2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12319683-B2 | Azabenzimidazole compounds and pharmaceutical | NIPPON SHINYAKU CO., LTD. (JP) | 2025-06-03 | — | — | US | disclosed |
| EP-3792260-B1 | AZABENZIMIDAZOLE COMPOUNDS AND PHARMACEUTICAL | NIPPON SHINYAKU CO LTD (JP) | 2024-09-11 | — | — | EP | disclosed |
| CN-112368282-B | Azabenzimidazole compounds and medicaments | 日本新药株式会社 | 2023-10-13 | — | — | CN | disclosed |