Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | ATM | Q13315 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30577906 | 1.00 | NPC1 (0.42) | NPC1RAB9AATMMAPTLMNA | |
| SCHEMBL2045035 | 0.85 | NPC1 (0.50) | NPC1RAB9AATMMAPTLMNA | |
| SCHEMBL3698912 | 0.85 | NPC1 (0.38) | NPC1RAB9AATMMAPTLMNA | |
| SCHEMBL28355617 | 0.85 | NPC1 (0.44) | NPC1RAB9AATMMAPTLMNA | |
| SCHEMBL28583461 | 0.85 | NPC1 (0.44) | NPC1RAB9AATMMAPTLMNA | |
| SCHEMBL29869681 | 0.84 | NPC1 (0.43) | NPC1RAB9AATMMAPTLMNA | |
| SCHEMBL9798037 | 0.82 | NPC1 (0.41) | NPC1RAB9AATMMAPTLMNA | |
| Bumetrizole SCHEMBL2398487 | 0.82 | NPC1 (0.53) | NPC1RAB9AATMMAPTLMNA | |
| Bumetrizole SCHEMBL8056551 | 0.82 | NPC1 (0.53) | NPC1RAB9AATMMAPTLMNA | |
| Bumetrizole SCHEMBL23734 | 0.82 | NPC1 (0.53) | NPC1RAB9AATMMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113518794-B | Addition-curable silicone adhesive composition | 迈图高新材料公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-116964133-A | Condensation curable composition comprising a siloxane-imide crosslinker | 迈图高新材料公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116917382-A | Siloxane-imide copolymer and addition-curable composition containing same | 迈图高新材料公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-116897179-A | Addition-curable composition comprising siloxane-imide copolymer | 迈图高新材料公司 | 2023-10-17 | — | — | CN | disclosed |
| CN-116888194-A | Condensation curable composition comprising a siloxane-imide base polymer | 迈图高新材料公司 | 2023-10-13 | — | — | CN | disclosed |