Bumetrizole

Bumetrizole

SCHEMBL23734

Cc1cc(-n2nc3ccc(Cl)cc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.53
RAB9A P51151 4/20 0.53
SMN1; SMN2 Q16637 4/20 0.44
ALDH1A1 P00352 4/20 0.44
POLB P06746 2/20 0.44
CA2 P00918 1/20 0.44
TYR P14679 1/20 0.44
LMNA P02545 1/20 0.40
HSPA5 P11021 1/20 0.38
CYP2C9 P11712 4/20 0.37
CYP2C19 P33261 4/20 0.37
HIF1A Q16665 3/20 0.37
MAPT P10636 4/20 0.35
KDM4E B2RXH2 3/20 0.35
ATM Q13315 2/20 0.35
CYP1A2 P05177 1/20 0.34
HPGD P15428 1/20 0.34
HSD17B10 Q99714 2/20 0.34
CYP2D6 P10635 1/20 0.34
TP53 P04637 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bumetrizole SCHEMBL8603228 1.00 NPC1 (0.53) NPC1RAB9ASMN1; SMN2ALDH1A1POLB
Bumetrizole SCHEMBL2398487 1.00 NPC1 (0.53) NPC1RAB9ASMN1; SMN2ALDH1A1POLB
Bumetrizole SCHEMBL8054070 1.00 NPC1 (0.53) NPC1RAB9ASMN1; SMN2ALDH1A1POLB
Bumetrizole SCHEMBL8056551 1.00 NPC1 (0.53) NPC1RAB9ASMN1; SMN2ALDH1A1POLB
Bumetrizole SCHEMBL29353083 1.00 NPC1 (0.53) NPC1RAB9ASMN1; SMN2ALDH1A1POLB
Bumetrizole SCHEMBL10836210 0.99 NPC1 (0.52) NPC1RAB9ASMN1; SMN2ALDH1A1POLB
Bumetrizole SCHEMBL6029618 0.99 NPC1 (0.52) NPC1RAB9ASMN1; SMN2ALDH1A1POLB
Bumetrizole SCHEMBL9273939 0.99 NPC1 (0.52) NPC1RAB9ASMN1; SMN2ALDH1A1POLB
Bumetrizole SCHEMBL9301984 0.99 NPC1 (0.52) NPC1RAB9ASMN1; SMN2ALDH1A1POLB
Bumetrizole SCHEMBL6068328 0.96 NPC1 (0.60) NPC1RAB9ASMN1; SMN2ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 75848 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146144-A1 SYNERGISTIC STABILIZER COMPOSITIONS AND METHODS FOR USING SAME FOR PROTECTING ORGANIC MATERIALS FROM UV LIGHT AND THERMAL DEGRADATION CYTEC INDUSTRIES INC. (US) 2026-05-28 US claimed
CN-119955290-B Wear-resistant drag chain and preparation method thereof Dongguan Wenchang electronic products Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122080544-A Alloy material based on PP-RCT and segmented PA6 and preparation method thereof 2026-05-26 CN claimed
CN-122060306-A Preparation method and application of dimer acid-based copolyester-based cold-resistant water-resistant adhesive material for automotive interiors 浙江澳宇新材料科技有限公司 2026-05-19 CN claimed
CN-122070479-A Ultrasonic indicating device and method for monitoring ultrasonic treatment JP实验室股份有限公司 2026-05-19 CN claimed
CN-119463777-B Long-acting mildew-proof joint beautifying agent and preparation method thereof 广州白云科技股份有限公司 2026-05-19 CN claimed
CN-122060339-A Anti-cracking ultraviolet aging-resistant modified asphalt and preparation method thereof 中国石油天然气股份有限公司 2026-05-19 CN claimed
CN-122060275-A Butadiene-styrene copolymer modified thermoplastic elastomer material 慈溪市山今高分子塑料有限公司 2026-05-19 CN claimed
CN-119286443-B High-permeability super-weather-resistant protective film and preparation method and application thereof 金发科技股份有限公司 2026-05-19 CN claimed
CN-122060251-A High-strength polypropylene material for sunshade net and preparation method thereof 石家庄怀斯贸易有限公司 2026-05-19 CN claimed
US-4269629-A A COMBINATION OF A HYDROXYBENZOTRIAZOLE, A PHENYLBENZOATE, AND A HINDERED PHENOLIC COMPOUND TO IMPART OXIDATION RESISTANCE; ULTRA VIOLET-RADIATION RESISTANCE; WEATHERPROOFING; MOLDING MATERIALS EASTMAN KODAK COMPANY (US) 1981-05-26 US claimed
US-4232103-A Phenyl benzotriazole stabilized photosensitive device XEROX CORPORATION (US) 1980-11-04 US claimed
US-4230867-A REDUCTION, CYCLIZATION OF NITROAZOBENZENES CIBA-GEIGY CORPORATION (US) 1980-10-28 US claimed
US-4219480-A REDUCTION OF UNDESIRED BY-PRODUCT AND EFFLUENT POLLUTION PROBLEMS CIBA-GEIGY CORPORATION (US) 1980-08-26 US claimed
US-4153780-A Process for the preparation of polycarbonate with weatherproof property IDEMITSU KOSAN COMPANY LIMITED (JP) 1979-05-08 US claimed
US-4141903-A REDUCTION AND CYCLIZATION OF THE CORRESPONDING O-NITROAZOBENZENES WITH CARBON MONOXIDE USING A COPPER-AMINE COMPLEX AS CATALYST CIBA-GEIGY CORPORATION (US) 1979-02-27 US claimed
US-4071975-A POLYISOBUTYLENE OXIDE, POLYOLEFIN; MULCHING FILM WHICH PHOTOLYTICALLY DEGRADES TO A POWDER DAICEL LTD. (JA) 1978-02-07 US claimed
US-4041044-A BY REDUCTION OF CORRESPONDING O-NITRO-AZOBENZENES WITH ZINC IN AQUEOUS ALKALI METAL HYDROXIDE CIBA-GEIGY CORPORATION (US) 1977-08-09 US claimed
US-3984541-A WHICH IMPEDE METAMORPHOSIS STAUFFER CHEMICAL COMPANY (US) 1976-10-05 US claimed
US-3935164-A NICKEL 3,5-DI-TERT-ALKYL 4-HYDROXYBENZOATE, AND A BENZOPHENONE OR BENZOTRIAZOLE CIBA-GEIGY CORPORATION (US) 1976-01-27 US claimed