Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bumetrizole SCHEMBL8603228 | 1.00 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| Bumetrizole SCHEMBL8054070 | 1.00 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| Bumetrizole SCHEMBL23734 | 1.00 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| Bumetrizole SCHEMBL8056551 | 1.00 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| Bumetrizole SCHEMBL29353083 | 1.00 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| Bumetrizole SCHEMBL10836210 | 0.99 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| Bumetrizole SCHEMBL6029618 | 0.99 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| Bumetrizole SCHEMBL9273939 | 0.99 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| Bumetrizole SCHEMBL9301984 | 0.99 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| Bumetrizole SCHEMBL6068328 | 0.96 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024053449-A1 | PHOTOCHROMIC PARTICLE AQUEOUS DISPERSION AND WATER-BASED INK COMPOSITION CONTAINING SAME | 三菱鉛筆株式会社 | 2024-03-14 | — | — | WO | disclosed |
| US-11364710-B2 | Composition, film, glass article, compound, high purity composition, method for producing compound, and method for producing film | FUJIFILM CORPORATION (JP) | 2022-06-21 | — | — | US | disclosed |
| EP-3636612-A1 | METHOD FOR REUSING INTERMEDIATE FILM FOR LAMINATED GLASS | Kuraray Co., Ltd. (JP) | 2020-04-15 | — | — | EP | disclosed |
| CN-105164175-B | Polyurethane, product and coating prepared therefrom and its manufacturing method | PPG工业俄亥俄公司 | 2019-06-04 | — | — | CN | disclosed |
| EP-3404055-A1 | COMPOSITION, FILM, GLASS ARTICLE, COMPOUND, HIGH PURITY COMPOSITION, METHOD FOR PRODUCING COMPOUND, AND METHOD FOR PRODUCING FILM | FUJIFILM Corporation (JP) | 2018-11-21 | — | — | EP | disclosed |
| US-20180311936-A1 | COMPOSITION, FILM, GLASS ARTICLE, COMPOUND, HIGH PURITY COMPOSITION, METHOD FOR PRODUCING COMPOUND, AND METHOD FOR PRODUCING FILM | FUJIFILM CORPORATION (JP) | 2018-11-01 | — | — | US | disclosed |
| CN-105308136-B | Fast curing aspartate polysiloxane hybrid coating | 科思创有限公司 | 2018-09-18 | — | — | CN | disclosed |
| CN-105031743-B | Recycled resin composition and the disposable medical instrument being produced from it | 贝克顿·迪金森公司 | 2018-06-26 | — | — | CN | disclosed |
| CN-108178876-A | Recycled resin composition and the disposable medical equipment being produced from it | 贝克顿·迪金森公司 | 2018-06-19 | — | — | CN | disclosed |
| EP-2697237-B1 | PLASTICIZERS AND OPTICAL FILMS | MERCK PATENT GMBH (DE) | 2016-03-02 | — | — | EP | disclosed |
| US-5250606-A | Polymer blend compositions containing a styrenic copolymer, an acetal polymer and a thermoplastic polyester or polycarbonate resin ingredient | THE DOW CHEMICAL COMPANY (US) | 1993-10-05 | — | — | US | disclosed |
| US-5244946-A | Styrenic copolymer/polyacetal/thermoplastic polyurethane or elastomeric copolyester blend compositions | THE DOW CHEMICAL COMPANY (US) | 1993-09-14 | — | — | US | disclosed |
| US-5196461-A | Molding material | THE DOW CHEMICAL COMPANY (US) | 1993-03-23 | — | — | US | disclosed |
| US-5061558-A | METHACRYLATE PROTECTIVE COATING CONTAINING A UV-ABSORBER FOR POLYCARBONATE | ROHM GMBH CHEMISCHE FABRIK (DE) | 1991-10-29 | — | — | US | disclosed |
| US-5025050-A | Including a 2-(2-hydroxyphenyl)benzotriazole, and a titanate | ETHYL CORPORATION (US) | 1991-06-18 | — | — | US | disclosed |
| US-5021485-A | Light stabilizer combination | CIBA-GEIGY CORPORATION (US) | 1991-06-04 | — | — | US | disclosed |
| US-4740542-A | Stabilization of high solids coatings with synergistic combinations | AMERICAN CYANAMID COMPANY (US) | 1988-04-26 | — | — | US | disclosed |
| US-4619956-A | MIXTURE OF PIPERDINE AND TRIAZINE COMPOUNDS | AMERICAN CYANAMID CO. (US) | 1986-10-28 | — | — | US | disclosed |
| US-4525504-A | 1,4-CYCLOHEXANDEICARBOXYLIC ACID AND 2,2,4,4-TETRAMETHYL-1,3-CYCLOBUTANEDIOL, UV AND HINDERED AMINE STABILIZERS | EASTMAN KODAK COMPANY (US) | 1985-06-25 | — | — | US | disclosed |
| US-4524165-A | 1,4-CYCLOHEXANEDICARBOXYLIC ACID AND 1,4-CYCLOHEXANE DIOL MONOMERS; POLYALKYLENE GLCOLS; STABILIZER MIXTURE | EASTMAN KODAK COMPANY (US) | 1985-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11364710-B2 | Composition, film, glass article, compound, high purity composition, method for producing compound, and method for producing film | SOST, VCL, CCNO | NPC1 3720/4885RAB9A 1907/4885SMN1; SMN2 2374/4885 |
| US-20180311936-A1 | COMPOSITION, FILM, GLASS ARTICLE, COMPOUND, HIGH PURITY COMPOSITION, METHOD FOR PRODUCING COMPOUND, AND METHOD FOR PRODUCING FILM | SOST, VCL, CCNO | NPC1 3720/4885RAB9A 1907/4885SMN1; SMN2 2374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.