Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 6/20 | 0.80 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.80 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | RXRG | P48443 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30646825 | 1.00 | CYP11B1 (0.80) | CYP11B1CYP11B2MAP4K4PTGS1AKR1C3 | |
| SCHEMBL29087719 | 0.87 | CYP11B1 (0.81) | CYP11B1CYP11B2MAP4K4MKNK1MKNK2 | |
| SCHEMBL30646799 | 0.87 | CYP11B1 (0.81) | CYP11B1CYP11B2MAP4K4MKNK1MKNK2 | |
| SCHEMBL30646820 | 0.85 | CYP11B1 (0.74) | CYP11B1CYP11B2PTGS1AKR1C3AKR1C2 | |
| SCHEMBL29087788 | 0.85 | CYP11B1 (0.74) | CYP11B1CYP11B2PTGS1AKR1C3AKR1C2 | |
| SCHEMBL491853 | 0.83 | PTGS1 (0.58) | CYP11B1CYP11B2PTGS1AKR1C3AKR1C2 | |
| SCHEMBL16675835 | 0.81 | CYP11B1 (0.78) | CYP11B1CYP11B2MAP4K4MKNK1MKNK2 | |
| SCHEMBL4217510 | 0.81 | KDM4E (0.68) | PTGS1AKR1C3AKR1C2KDM4EALDH1A1 | |
| SCHEMBL24499977 | 0.80 | CYP11B2 (0.57) | CYP11B1CYP11B2PTGS1PTGDR2RXRA | |
| SCHEMBL30530575 | 0.80 | CYP11B2 (0.57) | CYP11B1CYP11B2PTGS1PTGDR2RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710431-A | Small molecule compounds and compositions | 泰洛治疗公司 | 2023-09-05 | — | — | CN | disclosed |