Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12885826 | 0.94 | LMNA (0.84) | LMNACYP2C19HIF1AMAPTHPGD | |
| SCHEMBL8859007 | 0.90 | LMNA (0.77) | LMNACYP2C19HIF1AMAPTHPGD | |
| SCHEMBL709499 | 0.89 | LMNA (0.64) | LMNACYP2C19HIF1AHPGD | |
| SCHEMBL9009265 | 0.86 | LMNA (0.58) | LMNACYP2C19HIF1A | |
| Iopromide SCHEMBL29632300 | 0.86 | LMNA (1.00) | LMNACYP2C19HIF1AMAPTHPGD | |
| Iopromide SCHEMBL24546 | 0.86 | LMNA (1.00) | LMNACYP2C19HIF1AMAPTHPGD | |
| Iopromide SCHEMBL8845234 | 0.86 | LMNA (1.00) | LMNACYP2C19HIF1AMAPTHPGD | |
| SCHEMBL13309814 | 0.85 | LMNA (0.90) | LMNACYP2C19HIF1AHPGD | |
| SCHEMBL18931642 | 0.84 | LMNA (0.91) | LMNACYP2C19HIF1A | |
| SCHEMBL14864477 | 0.84 | LMNA (0.91) | LMNACYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116891420-A | Synthesis method of iopromide impurity D | 重庆圣华曦药业股份有限公司 | 2023-10-17 | — | — | CN | claimed |
| CN-116891420-A | Synthesis method of iopromide impurity D | 重庆圣华曦药业股份有限公司 | 2023-10-17 | — | — | CN | disclosed |
| CN-116891420-A | Synthesis method of iopromide impurity D | 重庆圣华曦药业股份有限公司 | 2023-10-17 | — | — | CN | disclosed |