Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.51 |
| ▸ | MDM4 | O15151 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29088261 | 0.87 | MAPT (0.69) | MAPTCYP1A2CYP2C9CYP2C19HDAC2 | |
| SCHEMBL29712862 | 0.85 | HDAC2 (0.71) | MAPTCYP1A2CYP2C9CYP2C19HDAC2 | |
| SCHEMBL8522637 | 0.85 | HDAC2 (0.71) | MAPTCYP1A2CYP2C9CYP2C19HDAC2 | |
| SCHEMBL6485998 | 0.82 | MAPT (0.77) | MAPTCYP1A2CYP2C9CYP2C19HDAC2 | |
| SCHEMBL5251492 | 0.82 | HDAC1 (0.66) | MAPTCYP1A2CYP2C9CYP2C19HDAC2 | |
| SCHEMBL403486 | 0.82 | HDAC1 (0.66) | MAPTCYP1A2CYP2C9CYP2C19HDAC2 | |
| SCHEMBL11591501 | 0.81 | HDAC1 (0.71) | MAPTCYP1A2CYP2C9CYP2C19HDAC2 | |
| SCHEMBL29226011 | 0.81 | MAPT (0.61) | MAPTCYP1A2CYP2C9CYP2C19HDAC2 | |
| SCHEMBL8528829 | 0.80 | MAPT (0.69) | MAPTCYP1A2CYP2C9CYP2C19HDAC2 | |
| SCHEMBL3529060 | 0.80 | MAPT (0.82) | MAPTCYP1A2CYP2C9CYP2C19HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112110877-B | Benzisoselenazolone derivative, preparation method and application thereof in anti-coronavirus medicament | 青岛大学 | 2023-09-08 | — | — | CN | disclosed |