Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | PLK1 | P53350 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | MDM4 | O15151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29088262 | 0.87 | MAPT (0.65) | MAPTCYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL11591501 | 0.85 | HDAC1 (0.71) | MAPTCYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL8528829 | 0.83 | MAPT (0.69) | MAPTCYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL3529060 | 0.83 | MAPT (0.82) | MAPTCYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL1548172 | 0.82 | MAPT (1.00) | MAPTCYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL8522637 | 0.81 | HDAC2 (0.71) | MAPTCYP1A2CYP2C9CYP2C19HDAC1 | |
| SCHEMBL29712862 | 0.81 | HDAC2 (0.71) | MAPTCYP1A2CYP2C9CYP2C19HDAC1 | |
| SCHEMBL10598787 | 0.81 | MAPT (0.66) | MAPTCYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL7752909 | 0.81 | MAPT (0.68) | MAPTCYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL27912234 | 0.80 | KCNMA1 (0.67) | MAPTCYP1A2CYP2C9CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112110877-B | Benzisoselenazolone derivative, preparation method and application thereof in anti-coronavirus medicament | 青岛大学 | 2023-09-08 | — | — | CN | disclosed |