Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28803930 | 0.85 | MAPT (0.52) | MAPTCYP1A2CYP2C9CYP2C19HDAC1 | |
| SCHEMBL11591501 | 0.85 | HDAC1 (0.71) | MAPTCYP1A2CYP2C9CYP2C19HDAC1 | |
| SCHEMBL14428130 | 0.84 | MAPT (0.57) | MAPTCYP1A2CYP2C9CYP2C19HDAC1 | |
| SCHEMBL5395767 | 0.84 | KMT2A (0.62) | MAPTCYP1A2CYP2C9CYP2C19HDAC1 | |
| SCHEMBL3529060 | 0.83 | MAPT (0.82) | MAPTCYP1A2CYP2C9CYP2C19HDAC1 | |
| SCHEMBL29088261 | 0.83 | MAPT (0.69) | MAPTCYP1A2CYP2C9CYP2C19HDAC1 | |
| SCHEMBL28589438 | 0.83 | MEN1 (0.67) | MAPTCYP1A2CYP2C9CYP2C19HDAC1 | |
| SCHEMBL22905311 | 0.83 | HDAC1 (0.71) | MAPTHDAC1MEN1KMT2AHDAC2 | |
| SCHEMBL10011045 | 0.83 | KCNMA1 (0.57) | MAPTHDAC1MEN1KMT2AHDAC2 | |
| SCHEMBL5178629 | 0.82 | HDAC1 (0.69) | MAPTCYP1A2CYP2C9CYP2C19HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197533-A1 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-08-23 | — | — | US | disclosed |
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-5834166-A | IMPROVED PHOTOSTABILITY | EASTMAN KODAK COMPANY (US) | 1998-11-10 | — | — | US | disclosed |
| US-4368257-A | DIACYLAMINO-TYPE COUPLER | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1983-01-11 | — | — | US | disclosed |
| US-4362810-A | DEVELOPMENT, SILVER HALIDE EMULSIONS | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1982-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197533-A1 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | DDC, DPP3, AMPD3 | MAPT 2536/4885CYP1A2 1210/4885CYP2C9 1056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.