Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | TYMP | P19971 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | MAP2 | P11137 | 2/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6472472 | 0.88 | HTT (0.40) | HTTCYP1A2LMNAMAPTALDH1A1 | |
| SCHEMBL26218697 | 0.85 | HTT (0.42) | HTTCYP1A2LMNAMAPTALDH1A1 | |
| SCHEMBL9844862 | 0.84 | HTT (0.37) | HTTCYP1A2LMNAMAPTALDH1A1 | |
| SCHEMBL29088482 | 0.83 | HTT (0.40) | HTTCYP1A2LMNAMAPTALDH1A1 | |
| SCHEMBL24511038 | 0.82 | LMNA (0.48) | HTTCYP1A2LMNAMAPTALDH1A1 | |
| SCHEMBL11304603 | 0.79 | LMNA (0.46) | HTTCYP1A2LMNAMAPTALDH1A1 | |
| SCHEMBL15655133 | 0.79 | LMNA (0.50) | HTTCYP1A2LMNAMAPTALDH1A1 | |
| SCHEMBL29097481 | 0.78 | HTT (0.40) | HTTCYP1A2LMNAMAPTALDH1A1 | |
| SCHEMBL11760118 | 0.77 | LMNA (0.43) | HTTCYP1A2LMNAMAPTALDH1A1 | |
| SCHEMBL142795 | 0.76 | LMNA (0.48) | HTTCYP1A2LMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116891403-A | Preparation method of 2,4' -difluorobenzophenone | 大连鼎燕医药化工有限公司 | 2023-10-17 | — | — | CN | disclosed |