Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 2/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | MAP2 | P11137 | 2/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29088482 | 0.86 | HTT (0.40) | HTTCYP1A2LMNAMAPTALDH1A1 | |
| SCHEMBL29097481 | 0.86 | HTT (0.40) | HTTCYP1A2LMNAMAPTALDH1A1 | |
| SCHEMBL29088481 | 0.84 | HTT (0.39) | HTTCYP1A2LMNAMAPTALDH1A1 | |
| SCHEMBL26218697 | 0.83 | HTT (0.42) | HTTCYP1A2LMNAMAPTALDH1A1 | |
| SCHEMBL7713106 | 0.80 | LMNA (0.48) | HTTCYP1A2LMNAMAPTALDH1A1 | |
| SCHEMBL247368 | 0.80 | LMNA (0.48) | HTTLMNAMAPTALDH1A1TYMP | |
| SCHEMBL6402127 | 0.78 | LMNA (0.46) | HTTLMNAMAPTALDH1A1TYMP | |
| SCHEMBL7704707 | 0.78 | LMNA (0.46) | HTTLMNAMAPTALDH1A1TYMP | |
| SCHEMBL7711087 | 0.77 | ALDH1A1 (0.50) | HTTCYP1A2LMNAMAPTALDH1A1 | |
| SCHEMBL15655133 | 0.77 | LMNA (0.50) | HTTCYP1A2LMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991013847-A1 | PROCESS FOR PREPARING CHLORO-DIFLUOROBENZENE | ISC CHEMICALS LIMITED (GB) | 1991-09-19 | — | — | WO | disclosed |
| EP-0447259-A1 | Process for preparing chloro-difluorobenzene | ISC CHEMICALS LIMITED (GB) | 1991-09-18 | — | — | EP | disclosed |