Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 20/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26128080 | 0.92 | AGTR2 (0.64) | AGTR2CYP3A4 | |
| SCHEMBL26130559 | 0.90 | AGTR2 (0.65) | AGTR2CYP3A4 | |
| SCHEMBL26130116 | 0.90 | AGTR2 (0.84) | AGTR2CYP3A4AGTR1 | |
| SCHEMBL29088539 | 0.90 | AGTR2 (0.63) | AGTR2CYP3A4 | |
| SCHEMBL26129539 | 0.87 | AGTR2 (0.56) | AGTR2CYP3A4 | |
| SCHEMBL29088507 | 0.86 | AGTR2 (0.53) | AGTR2CYP3A4AGTR1 | |
| SCHEMBL26127924 | 0.86 | AGTR2 (0.55) | AGTR2AGTR1 | |
| SCHEMBL26128705 | 0.85 | AGTR2 (0.55) | AGTR2CYP3A4 | |
| SCHEMBL26129782 | 0.85 | AGTR2 (0.66) | AGTR2CYP3A4 | |
| SCHEMBL29088513 | 0.85 | AGTR2 (0.55) | AGTR2CYP3A4AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250214978-A1 | AT2R AGONIST | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company (CN) | 2025-07-03 | — | — | US | disclosed |
| EP-4506345-A1 | AT2R AGONIST | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company (CN) | 2025-02-12 | — | — | EP | disclosed |
| CN-116891464-A | AT2R agonist | 武汉人福创新药物研发中心有限公司 | 2023-10-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250214978-A1 | AT2R AGONIST | AGTR1, AGTR2, AVPR2 | AGTR2 2/4885CYP3A4 1748/4885AGTR1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.