Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 19/20 | 0.49 |
| ▸ | NTRK3 | Q16288 | 10/20 | 0.49 |
| ▸ | NTRK2 | Q16620 | 8/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21510296 | 1.00 | NTRK1 (0.49) | NTRK1NTRK3NTRK2SCN9A | |
| SCHEMBL29088981 | 0.88 | NTRK1 (0.47) | NTRK1NTRK3NTRK2SCN9A | |
| SCHEMBL23083841 | 0.88 | NTRK1 (0.45) | NTRK1NTRK3NTRK2 | |
| SCHEMBL16947092 | 0.88 | NTRK1 (0.46) | NTRK1NTRK3NTRK2SCN9A | |
| SCHEMBL23083891 | 0.86 | NTRK1 (0.51) | NTRK1NTRK3NTRK2 | |
| SCHEMBL21229311 | 0.85 | SCN9A (0.42) | NTRK1SCN9A | |
| Trifluoroacetic Acid SCHEMBL30512188 | 0.85 | NTRK1 (0.51) | NTRK1NTRK3NTRK2 | |
| SCHEMBL21510292 | 0.85 | NTRK1 (0.53) | NTRK1NTRK3NTRK2 | |
| SCHEMBL21510311 | 0.83 | NTRK1 (0.57) | NTRK1NTRK3NTRK2 | |
| SCHEMBL21510573 | 0.83 | NTRK1 (0.52) | NTRK1NTRK3NTRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156813-B | Heterocyclic compounds as TRK inhibitors | 北京诺诚健华医药科技有限公司 | 2023-07-25 | — | — | CN | disclosed |