Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 4/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | F11 | P03951 | 15/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 15/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30656500 | 1.00 | FLT3 (0.47) | FLT3GSK3BF11KLKB1CYP3A4 | |
| SCHEMBL29479321 | 0.84 | F11 (0.49) | F11KLKB1CYP3A4 | |
| SCHEMBL21357358 | 0.84 | F11 (0.49) | F11KLKB1CYP3A4 | |
| SCHEMBL30656460 | 0.83 | FLT3 (0.48) | FLT3GSK3BF11KLKB1MIF | |
| SCHEMBL29089479 | 0.83 | FLT3 (0.48) | FLT3GSK3BF11KLKB1MIF | |
| SCHEMBL30656621 | 0.82 | BRAF (0.39) | F11KLKB1CYP3A4 | |
| SCHEMBL29089496 | 0.82 | BRAF (0.39) | F11KLKB1CYP3A4 | |
| SCHEMBL29089481 | 0.82 | F11 (0.40) | F11KLKB1CYP3A4 | |
| SCHEMBL30656620 | 0.82 | F11 (0.40) | F11KLKB1CYP3A4 | |
| SCHEMBL24633283 | 0.80 | F11 (0.53) | F11KLKB1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116903585-A | Oxo-pyridine derivative and application thereof in medicine | 天津药物研究院有限公司 | 2023-10-20 | — | — | CN | disclosed |